Evidence map›Paper›PMID 19180149›Full record

ArticleKidney international2009

Collapsing glomerulopathy: beyond serendipity in mouse genetics.

Peter J Nelson, Leslie A Bruggeman

Abstract readComment
In one paragraph

Article in Kidney international, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Peter J NelsonDivision of Nephrology, Smilow Research Center, New York University School of Medicine, New York, NY 10016, USA. peter.nelson2@nyumc.org
Leslie A Bruggeman

Funding

Transcriptional regulation in chronic renal disease pathogenesisR01DK061395 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI BRUGGEMAN, LESLIE A · 2001 to 2008
$1.6M
NIDDK NIH HHS R01 DK061395
6 · The paper itself

Abstract

Clinical correlates suggest that collapsing glomerulopathy results from the pathogenic interaction between patients' intractable genetic susceptibilities and environmental insults. When the environmental insults include a virus that introduces its own pathogenic genes, the interactions become more complex. Chan et al. combine reverse and forward genetic techniques in mice toward understanding this complexity with HIV and identify candidate genetic modifiers of collapsing glomerulopathy.

Indexed as

Genetic Predisposition to DiseaseAnimalsEnvironmentGlomerulonephritisHIV InfectionsHumansMice

Identifiers

PMID19180149
PMCPMC2787237

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.