ArticleCell cycle (Georgetown, Tex.)2009
Handcuff for sisters: a new model for sister chromatid cohesion.
Article in Cell cycle (Georgetown, Tex.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Article
- Role of chromosomal cohesion and separation in aneuploidy and tumorigenesis.Cellular and molecular life sciences : CMLS · 2024Review
- Integrated Multi-omics Analyses Identify CDCA5 as a Novel Biomarker Associated with Alternative Splicing, Tumor Microenvironment, and Cell Proliferation in Colon Cancer Via Pan-cancer Analysis.Journal of Cancer · 2024Article
- The Comprehensive Analysis Illustrates the Role of CDCA5 in Breast Cancer: An Effective Diagnosis and Prognosis Biomarker.International journal of genomics · 2023Article
- It's all in the numbers: Cohesin stoichiometry.Frontiers in molecular biosciences · 2022Review
- Deciphering cervical cancer-associated biomarkers by integrated multi-omics approach.American journal of translational research · 2022Article
- CDCA5 promotes the progression of prostate cancer by affecting the ERK signalling pathway.Oncology reports · 2021Article
- Review
- Article
- Brca2, Pds5 and Wapl differentially control cohesin chromosome association and function.PLoS genetics · 2018Article
- Superresolution microscopy reveals the three-dimensional organization of meiotic chromosome axes in intactProceedings of the National Academy of Sciences of the United States of America · 2017Article
- Structural Insights into Ring Formation of Cohesin and Related Smc Complexes.Trends in cell biology · 2016Review
- CDCA5 overexpression is an indicator of poor prognosis in patients with urothelial carcinomas of the upper urinary tract and urinary bladder.American journal of translational research · 2015Article
- Linking chromosome duplication and segregation via sister chromatid cohesion.Methods in molecular biology (Clifton, N.J.) · 2014Review
- Article
- Sororin is a master regulator of sister chromatid cohesion and separation.Cell cycle (Georgetown, Tex.) · 2012Review
- Article
- Epitope tag-induced synthetic lethality between cohesin subunits and Ctf7/Eco1 acetyltransferase.FEBS letters · 2010Article
- Both interaction surfaces within cohesin's hinge domain are essential for its stable chromosomal association.Current biology : CB · 2010Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
High fidelity chromosome transmission requires the pairing of sister chromatids by a group of conserved proteins called cohesins during S-phase. Sister chromatid cohesion is maintained until anaphase onset. Presently, there are two sets of models of cohesin complex popular in the cohesin biology field: one model predicts that single cohesin rings entrap both sister chromatids, and the other model proposes that cohesin complexes associate with each sister chromatid and become paired during DNA replication. It is the first model that currently predominate the field--in part because prior efforts failed to detect higher order cohesin-cohesin interactions. However, the static configuration and size limitation of the one ring embrace model are the major limitations of the embrace model, and cannot explain various functions of cohesin in DNA replication, DNA repair and gene expression. In a recent study published by Zhang et al. in the Journal of Cell Biology describes a two-ring handcuff model for the cohesin complex, and provides new information regarding how sister chromatid cohesion and separation are achieved in vertebrate cell systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.