Evidence map›Paper›PMID 19175559›Full record

ReviewTransplant international : official journal of the European Society for Organ Transplantation2009

Noncognate function of B cells in transplantation.

Samuel J Balin, Jeffrey L Platt, Marilia Cascalho

Erratum issuedAbstract readReview
In one paragraph

Review in Transplant international : official journal of the European Society for Organ Transplantation, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Antibodies in transplantation.Discovery medicine · 2010
    Review
  2. Transplantation immunology: solid organ and bone marrow.The Journal of allergy and clinical immunology · 2010
    Review
  3. Effect of end-stage renal disease on B-lymphocyte subpopulations, IL-7, BAFF and BAFF receptor expression.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2010
    Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

3 authors.

Samuel J BalinDepartment of Surgery and Microbiology, University of Michigan, Ann Arbor, MI 48109, USA.
Jeffrey L Platt
Marilia Cascalho

Funding

T cell responses and cardiac transplantation in infancyP01HL079067 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PLATT, JEFFREY L · 2005 to 2009
$6.3M
Xenogeneic Natural Antibody Targets-Structure/FunctionR37HL052297 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PLATT, JEFFREY L · 2001 to 2010
$3.9M
XENOGENEIC NATURAL ANTIBODY TARGETS--STRUCTURE/FUNCTIONR01HL052297 · NHLBI · MAYO CLINIC COLL OF MEDICINE, ROCHESTER · PI PLATT, JEFFREY L · 1993 to 2000
$319k
NHLBI NIH HHS HL52297NHLBI NIH HHS HL79067NHLBI NIH HHS P01 HL079067NHLBI NIH HHS R37 HL052297
6 · The paper itself

Abstract

How B cells affect the outcome of transplants is a question of enduring interest. Initial efforts to answer that question suggested, wrongly, that B cells have no impact on transplantation. Now, however, B cells are known to influence not only the outcome of vascularized grafts through the production of anti-donor antibodies but also the competence of cellular immunity through a number of physiologic functions. In this study, we explain why the importance of B cells was overlooked in the past and consider the range of noncognate functions of B cells that may determine the outcome of transplants.

Indexed as

Antigen PresentationB-LymphocytesCytokinesGraft RejectionGraft SurvivalHumansT-LymphocytesTransplantation, HomologousCytokines

Identifiers

PMID19175559
PMCPMC2882152

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.