ArticleNeurocase2009
Neurocognitive functioning of a child with partial trisomy 6 and monosomy 21.
Article in Neurocase, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01256229 (OUTCOMES IN CHILDREN WITH DEVELOPMENTAL DELAY AND DEAFNESS), which is not on this map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Outcomes in children with developmental delay and deafness: a prospective, randomized trial
Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Monosomy chromosome 21 compensated by 21q22.11q22.3 duplication in a case with small size and minor anomalies.Molecular cytogenetics · 2018Article
- Functional near-infrared spectroscopy for neuroimaging in cochlear implant recipients.Hearing research · 2016Review
- Proximal 21q deletion as a result of a de novo unbalanced t(12;21) translocation in a patient with dysmorphic features, hepatomegaly, thick myocardium and delayed psychomotor development.Molecular cytogenetics · 2016Article
- Modeling partial monosomy for human chromosome 21q11.2-q21.1 reveals haploinsufficient genes influencing behavior and fat deposition.PloS one · 2012Article
- Neuroimaging with near-infrared spectroscopy demonstrates speech-evoked activity in the auditory cortex of deaf children following cochlear implantation.Hearing research · 2010Article
- Deficiencies in the region syntenic to human 21q22.3 cause cognitive deficits in mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
This case study describes the neurocognitive presentation of a child with identified genetic abnormalities of trisomy 6 and monosomy 21 who was evaluated as part of a standard medical protocol for cochlear implantation following diagnosis of profound sensorineural hearing loss. This child received neurocognitive testing prior to cochlear implantation and approximately 12 months post-activation of his cochlear implant. While he has not fully developed oral language, his presentation suggested improvement in overall skills since the activation of the cochlear implant; however, less than would be expected for a typically developing child.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.