ArticleWorld journal of pediatrics : WJP2009
Why we are still doing so many exchange blood transfusion for neonatal jaundice in Nigeria.
Article in World journal of pediatrics : WJP, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers, 2 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- Transcutaneous bilirubinometry for detecting jaundice in term or late preterm neonates.The Cochrane database of systematic reviews · 2024Pooled it
- Transcutaneous bilirubinometry versus total serum bilirubin measurement for newborns.The Cochrane database of systematic reviews · 2023Pooled it
- Trial
- Neonatal jaundice: magnitude of the problem in Cairo University's neonatal intensive Care unit as a referral center.African health sciences · 2023Article
- Community health worker-led household screening and management of neonatal hyperbilirubinemia in rural Bangladesh: a cluster randomized control trial protocol.Gates open research · 2023Article
- Understanding the risk factors for adverse events during exchange transfusion in neonatal hyperbilirubinemia using explainable artificial intelligence.BMC pediatrics · 2022Article
- Challenges and recommendations to improve implementation of phototherapy among neonates in Malawian hospitals.BMC pediatrics · 2022Article
- Causes of severe neonatal hyperbilirubinemia: a multicenter study of three regions in China.World journal of pediatrics : WJP · 2021Observational
- Pattern of serum bilirubin changes following double volume exchange blood transfusion in neonates at a tertiary health facility in Nigeria.The Pan African medical journal · 2021Article
- Neonatal Hyperbilirubinemia treatment by Locally Made Low-Cost Phototherapy Units.Ethiopian journal of health sciences · 2021Article
- Neonatal Jaundice: Perception of Pregnant Women Attending Antenatal Clinic at a Tertiary Hospital in Southwest, Nigeria.Global pediatric health · 2020Article
- Neonatal Jaundice: awareness, perception and preventive practices in expectant mothers.Ghana medical journal · 2019Article
- Patterns of acute bilirubin encephalopathy in Nigeria: a multicenter pre-intervention study.Journal of perinatology : official journal of the California Perinatal Association · 2018Article
- A Survey of Practice and Knowledge of Refugee and Migrant Pregnant Mothers Surrounding Neonatal Jaundice on the Thailand-Myanmar Border.Journal of tropical pediatrics · 2017Article
- Burden of severe neonatal jaundice: a systematic review and meta-analysis.BMJ paediatrics open · 2017Article
- Glucose-6-Phosphate Dehydrogenase Deficiency and the Need for a Novel Treatment to Prevent Kernicterus.Clinics in perinatology · 2016Review
- Exchange Transfusion for Severe Neonatal Hyperbilirubinemia: 17 Years' Experience from Vojvodina, Serbia.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2016Article
- Facility-based constraints to exchange transfusions for neonatal hyperbilirubinemia in resource-limited settings.World journal of clinical pediatrics · 2016Review
- Heliotherapy for Neonatal Hyperbilirubinemia in Southwest, Nigeria: A Baseline Pre-Intervention Study.PloS one · 2016Observational
- Evaluation of a simple intervention to reduce exchange transfusion rates among inborn and outborn neonates in Myanmar, comparing pre- and post-intervention rates.BMC pediatrics · 2015Article
Corrections and comments
- Erratum issuedOgunlesi, Titus A [corrected to Ogunlesi, Tinuade A]
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince exchange blood transfusion (EBT) is associated with serious complications, phototherapy has been made more powerful to reduce the need for EBT in the developed world. This study was undertaken to determine the indications for EBT in neonatal jaundice (NNJ) at our unit and what proportion of EBTs was possibly avoidable.
methodsAll the babies who had EBT for hyperbilirubinemia over a three-year period were included. Age, sex, weight, place of delivery, blood group of baby and mother, other investigations, management, and the outcome of the babies were recorded.
resultsOf the 1686 babies admitted to the neonatal unit, 90 (5.3%) had EBT. Fourteen (15.6%) were inborn while 76 (84.4%) were out-born babies. Fifty-six (62.2%) babies were admitted primarily for NNJ while 34 (37.8%) developed NNJ during admission. Thirty-six (40.0%) of the babies had phototherapy for more than 24 hours prior to EBT either because they were of very low birthweight or NNJ was detected very early and therapy was so commenced. Sixty-eight (75.6%) babies had single EBT while the remaining 22 (24.4%) had two sessions of EBT. Factors associated with severe NNJ in babies requiring EBT included low birthweight (<2500 g, 44.4%), ABO incompatibility (30.0%), glucose-6-phosphate dehydrogenase deficiency (34.4%) and septicemia (26.1%). Twenty-seven (30.0%) of the neonates developed features of kernicterus: 26 before admission while 1 during admission; all except one were delivered outside the hospital.
conclusionsThe EBT rate in our center was high. With more effective phototherapy, EBT could be avoided in most of the babies who initially had phototherapy for more than 24 hours before EBT and repeated EBT sessions. Health education of the population at risk, especially pregnant women, and early referral at the primary health care level will reduce the burden of severe NNJ.
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