ReviewNature reviews. Microbiology2009
A new perspective on radiation resistance based on Deinococcus radiodurans.
Review in Nature reviews. Microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 215 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
215 citing papers in PubMed, 480 citations in OpenAlex.
- Molecular hydrogen: a potential guardian against environmental radiation damage.Medical gas research · 2027Review
- Biological contributions to manganese oxides in rock varnish at Murujuga (Western Australia).Scientific reports · 2026Article
- Rising from the fragments: a multi-factorial regulatory framework of DNA damage response in Deinococcus radiodurans.Extremophiles : life under extreme conditions · 2026Review
- Complete genome sequence of Bacillus pseudomycoides CHAES I 2_2, a PHA-producing bacterium isolated from benthal deposits of the chornobyl NPP water cooling pond.BMC genomic data · 2026Article
- DrPitA-mediated enrichment of intracellular manganese and phosphate contributes to oxidative stress resistance ofApplied and environmental microbiology · 2026Article
- Radiation-Resistant Microbes: Pioneers for Life Beyond Earth.Current microbiology · 2026Review
- Extremophile survives the transient pressures associated with impact-induced ejection from Mars.PNAS nexus · 2026Article
- Geochemical, radiological, and heat-production characteristics of the ElGara granitoids (Southwestern Desert).Scientific reports · 2026Article
- Horizontal transfer of post-translational modifiers brings evolutionary opportunity and challenges to a conserved translation factor.BMC biology · 2026Article
- Physiological Changes and Transposition of Insertion Sequences in theInternational journal of molecular sciences · 2026Article
- Life resists chemistry not conditions.FEMS microbes · 2026Article
- Genomic signatures of radiation stress adaptations inFrontiers in microbiology · 2026Article
- Elucidating the interplay between intracellular manganese-iron-ratio and radiotolerance across all domains of life.FEMS microbes · 2026Article
- Evaluating the scientific and regulatory case for the deployment of the radioresistant genusFrontiers in microbiology · 2026Review
- Article
- Drosophila melanogaster: an old and future ally to radiobiology.Journal of radiation research · 2025Review
- The role of extremophile microbiomes in terraforming Mars.Communications biology · 2025Review
- Metal-induced biofilm formation by radiation resistant bacteria Deinococcus radiodurans and Deinococcus indicus.Extremophiles : life under extreme conditions · 2025Article
- Designer probiotic-based living drugs for uric acid homeostasis control in hyperuricemic mice and rats.Cell reports. Medicine · 2025Article
- The Role of the MntABC Transporter System in the Oxidative Stress Resistance ofInternational journal of molecular sciences · 2025Article
155 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In classical models of radiation toxicity, DNA is the molecule that is most affected by ionizing radiation (IR). However, recent data show that the amount of protein damage caused during irradiation of bacteria is better related to survival than to DNA damage. In this Opinion article, a new model is presented in which proteins are the most important target in the hierarchy of macromolecules affected by IR. A first line of defence against IR in extremely radiation-resistant bacteria might be the accumulation of manganese complexes, which can prevent the production of iron-dependent reactive oxygen species. This would allow an irradiated cell to protect sufficient enzymatic activity needed to repair DNA and survive.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.