ReviewHuman heredity2009
Haplotyping methods for pedigrees.
Review in Human heredity, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Genetic and Molecular Determinants of Familial Transmission of Skeletal Malocclusions.Orthodontics & craniofacial research · 2025Review
- Sister haplotypes and recombination disequilibrium: a new approach to identify associations of haplotypes with complex diseases.Frontiers in genetics · 2023Article
- The Contribution ofInternational journal of molecular sciences · 2022Review
- flopp: Extremely Fast Long-Read Polyploid Haplotype Phasing by Uniform Tree Partitioning.Journal of computational biology : a journal of computational molecular cell biology · 2022Article
- Article
- scHaplotyper: haplotype construction and visualization for genetic diagnosis using single cell DNA sequencing data.BMC bioinformatics · 2020Article
- Rediscovering the value of families for psychiatric genetics research.Molecular psychiatry · 2019Review
- Curiosities of X chromosomal markers and haplotypes.International journal of legal medicine · 2018Article
- Family-based approaches: design, imputation, analysis, and beyond.BMC genetics · 2016Article
- GenomeLaser: fast and accurate haplotyping from pedigree genotypes.Bioinformatics (Oxford, England) · 2015Article
- Molecular characterization of a long range haplotype affecting protein yield and mastitis susceptibility in Norwegian Red cattle.BMC genetics · 2011Article
- Family-based designs for genome-wide association studies.Nature reviews. Genetics · 2011Review
- The importance of phase information for human genomics.Nature reviews. Genetics · 2011Review
- Estimation and visualization of identity-by-descent within pedigrees simplifies interpretation of complex trait analysis.Human heredity · 2011Article
- Haplotype association analyses in resources of mixed structure using Monte Carlo testing.BMC bioinformatics · 2010Article
- A haplotype inference algorithm for trios based on deterministic sampling.BMC genetics · 2010Article
- Rapid haplotype inference for nuclear families.Genome biology · 2010Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Haplotypes provide valuable information in the study of diseases, complex traits, population histories, and evolutionary genetics. With the dramatic increase in the number of available single nucleotide polymorphism (SNP) markers, haplotype inference (haplotyping) using observed genotype data has become an important component of genetic studies in general and of statistical gene mapping in particular. Existing haplotyping methods include (1) population-based methods, (2) methods for pooled DNA samples, and (3) methods for family and pedigree data. The methods and computer programs for population data and pooled DNA samples were reviewed recently in the literature. As several authors noted, family and pedigree datasets are abundant and have unique advantages. In the past twenty years, many haplotyping methods for family and pedigree data have been developed. Therefore, in this contribution we review haplotyping methods and the corresponding computer programs suitable for family and pedigree data and discuss their applications and limitations. We explore the connections among these methods, and describe the challenges that remain to be addressed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.