Evidence map›Paper›PMID 19171801›Full record

ArticleAntimicrobial agents and chemotherapy2009

Activity of posaconazole and other antifungal agents against Mucorales strains identified by sequencing of internal transcribed spacers.

Ana Alastruey-Izquierdo, Maria Victoria Castelli, Isabel Cuesta, Araceli Monzon, Manuel Cuenca-Estrella, Juan Luis Rodriguez-Tudela

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. In vitro combination with doxycycline plus antifungals against clinical Mucorales pathogens.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  8. Article
  9. Review
  10. Review
  11. Focusing COVID-19-associated mucormycosis: a major threat to immunocompromised COVID-19.Environmental science and pollution research international · 2023
    Review
  12. Article
  13. Review
  14. First reported case of Gilbertella persicaria in human stool: outcome of a community study from Segamat, Johor, Malaysia.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Article
  15. A Revised Species Concept for OpportunisticAntimicrobial agents and chemotherapy · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana Alastruey-IzquierdoServicio de Micologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Spain.
Maria Victoria Castelli
Isabel Cuesta
Araceli Monzon
Manuel Cuenca-Estrella
Juan Luis Rodriguez-Tudela

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antifungal susceptibility profiles of 77 clinical strains of Mucorales species, identified by internal transcribed spacer sequencing, were analyzed. MICs obtained at 24 and 48 h were compared. Amphotericin B was the most active agent against all isolates, except for Cunninghamella and Apophysomyces isolates. Posaconazole also showed good activity for all species but Cunninghamella bertholletiae. Voriconazole had no activity against any of the fungi tested. Terbinafine showed good activity, except for Rhizopus oryzae, Mucor circinelloides, and Rhizomucor variabilis isolates.

Indexed as

Amphotericin BAntifungal AgentsDNA, Ribosomal SpacerMicrobial Sensitivity TestsMucoralesTriazolesAmphotericin BAntifungal AgentsDNA, Ribosomal SpacerposaconazoleTriazoles

Identifiers

PMID19171801
PMCPMC2663095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.