ArticleAntimicrobial agents and chemotherapy2009
Accelerated metabolism of voriconazole and its partial reversal by cimetidine.
Article in Antimicrobial agents and chemotherapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 34 citations in OpenAlex.
- Voriconazole therapeutic drug monitoring: results of a prematurely discontinued randomized multicenter trial.Transplant infectious disease : an official journal of the Transplantation Society · 2015Trial
- Application of modified Michaelis - Menten equations for determination of enzyme inducing and inhibiting drugs.BMC pharmacology & toxicology · 2021Article
- A Collaborative Tale of Diagnosing and Treating Chronic Pulmonary Aspergillosis, from the Perspectives of Clinical Microbiologists, Surgical Pathologists, and Infectious Disease Clinicians.Journal of fungi (Basel, Switzerland) · 2020Review
- A suspected case of autoinduction of voriconazole metabolism in a patient with cerebral aspergillosis.Drug, healthcare and patient safety · 2017Article
- Successful Treatment of Allergic Bronchopulmonary Aspergillosis With Isavuconazole: Case Report and Review of the Literature.Open forum infectious diseases · 2017Article
- Longitudinal Analysis of the Effect of Inflammation on Voriconazole Trough Concentrations.Antimicrobial agents and chemotherapy · 2016Article
- Inflammation is associated with voriconazole trough concentrations.Antimicrobial agents and chemotherapy · 2014Article
- Aspergillus osteomyelitis: epidemiology, clinical manifestations, management, and outcome.The Journal of infection · 2014Review
- A reference laboratory experience of clinically achievable voriconazole, posaconazole, and itraconazole concentrations within the bloodstream and cerebral spinal fluid.Antimicrobial agents and chemotherapy · 2014Article
- What can we learn and what do we need to know amidst the iatrogenic outbreak of Exserohilum rostratum meningitis?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013Article
- Locally extensive angio-invasive Scedosporium prolificans infection following resection for squamous cell lung carcinoma.Medical mycology case reports · 2013Article
- Update on the optimal use of voriconazole for invasive fungal infections.Infection and drug resistance · 2011Article
- What is the role of therapeutic drug monitoring in antifungal therapy?Current infectious disease reports · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
We report a case of accelerated metabolism of voriconazole during therapy for invasive pulmonary aspergillosis, resulting in subtherapeutic levels. Target voriconazole levels were restored with high dosages of voriconazole (up to 40 mg/kg of body weight/day) and the addition of cimetidine as a cytochrome P450 enzyme inhibitor.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.