ReviewCurrent rheumatology reports2009
The biomechanics of osteoarthritis: implications for therapy.
Review in Current rheumatology reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- The PICO project: aquatic exercise for knee osteoarthritis in overweight and obese individuals.BMC musculoskeletal disorders · 2013Trial
- Simulated gait training improves joint loading symmetry in unilateral transfemoral bone-anchored limb users.Journal of biomechanics · 2026Article
- Transfemoral bone-anchored limb use changes dynamic hip muscle forces during walking.Journal of biomechanics · 2025Article
- Unilateral transfemoral osseointegrated prostheses improve joint loading during walking.Journal of biomechanics · 2023Article
- Discharging the medial knee compartment: comparison of pressure distribution and kinematic shifting after implantation of an extra-capsular absorber system (ATLAS) and open-wedge high tibial osteotomy-a biomechanical in vitro analysis.Archives of orthopaedic and trauma surgery · 2023Article
- Effects of Hip Bracing on Gait Biomechanics, Pain and Function in Subjects With Mild to Moderate Hip Osteoarthritis.Frontiers in bioengineering and biotechnology · 2022Article
- Biomechanical Study of a Tricompartmental Unloader Brace for Patellofemoral or Multicompartment Knee Osteoarthritis.Frontiers in bioengineering and biotechnology · 2020Article
- High tibial osteotomy increases patellofemoral pressure if adverted proximal, while open-wedge HTO with distal biplanar osteotomy discharges the patellofemoral joint: different open-wedge high tibial osteotomies compared to an extra-articular unloading device.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019Article
- Two compartment pharmacokinetic model describes the intra-articular delivery and retention of rhprg4 following ACL transection in the Yucatan mini pig.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019Article
- Comparison of the efficiency of an extra-articular absorber system and high tibial osteotomy for unloading the medial knee compartment: an in vitro study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2017Article
- Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use.Osteoarthritis and cartilage · 2015Review
- Safety and Feasibility of a KineSpring Knee System for the Treatment of Osteoarthritis: A Case Series.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2015Article
- Early knee osteoarthritis management should first address mechanical joint overload.Orthopedic reviews · 2014Review
- Conservative management of symptomatic knee osteoarthritis: a flawed strategy?Orthopedic reviews · 2013Article
- Midterm Outcomes and Predictors of Clinical Success With the KineSpring Knee Implant System.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2013Article
- Article
- Successful two-stage revision of a KineSpring® joint unloading implant: a case study.International medical case reports journal · 2012Article
- Knee Osteoarthritis Treatment with the KineSpring Knee Implant System: A Report of Two Cases.Case reports in orthopedics · 2012Article
- Asymmetric loading and bone mineral density at the asymptomatic knees of patients with unilateral hip osteoarthritis.Arthritis and rheumatism · 2011Article
- Unload it: the key to the treatment of knee osteoarthritis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pathophysiology of osteoarthritis (OA) has been extensively studied. However, the basic approach to therapy, which consists of pain relief and maintenance of function, has not changed for decades. At present, there are no nonsurgical methods that clearly interfere with the natural history of OA or provide prolonged pain palliation. Much of OA disease progression is mediated by aberrant biomechanical forces or through pathologic responses to those forces. As understanding of these mechanisms improves, novel therapeutic approaches are being studied that may provide prolonged reductions in loading of OA joints. These new therapies may ultimately be shown to retard disease progression and palliate pain. This article reviews some of these strategies.
Indexed as
Identifiers
19171107What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.