ArticleBMC musculoskeletal disorders2009
Depression and anxiety as major determinants of neck pain: a cross-sectional study in general practice.
Article in BMC musculoskeletal disorders, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 50 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Cervical Mobility on Cardiovascular And Respiratory Outcomes Among Young Adults
The Effect of Different Electrotherapy Interventions on Pain and Hand Function in Young Individuals With Neck Pain: a Randomized Controlled Double-blind Trial
Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it, 137 citations in OpenAlex.
- The influence of informal social support on risk and prognosis in spinal pain: a systematic review.European journal of pain (London, England) · 2011Pooled it
- Effects of Manual Therapy on Fatigue, Pain, and Psychological Aspects in Women with Fibromyalgia.International journal of environmental research and public health · 2020Trial
- Trial
- Effects of three different conservative treatments on pain, disability, quality of life, and mood in patients with cervical spondylosis.Rheumatology international · 2012Trial
- Cognitive functional therapy for persistent neck pain.Pain management · 2026Article
- Article
- Neuro-immune contributors to persistent musculoskeletal pain: from mechanisms to clinical assessment and management.Musculoskeletal science & practice · 2026Review
- Relationship between anxiety symptoms and cervical motor control in individuals without diagnosed psychiatric or neurological disorders.Frontiers in psychology · 2026Article
- Nociplastic, neuropathic and nociceptive neck pain should be differentiated based on comprehensive examinations rather than pain scales.Saudi medical journal · 2025Article
- Chronic neck pain as an exacerbating factor for depressive symptoms in a 1-Year longitudinal population study.Scientific reports · 2025Article
- Cross-Cultural Adaptation, Reliability, and Validity of the Greek Version of the Fremantle Neck Awareness Questionnaire (FreNAQ-GR) in Patients with Chronic Neck Pain.Healthcare (Basel, Switzerland) · 2024Article
- Intra-rater and Inter-rater Reliability of the Commander Pressure Algometer in Greek Patients With Chronic Neck Pain.Cureus · 2024Article
- Prevalence, Activity Limitations and Quality of Life in Patients with Non-Specific Neck Pain in Burundi: A Cross-Sectional Study.Journal of pain research · 2024Article
- Assessment of Long-term Effects of Adding Osteopathic Manipulative Treatment to Neck Exercises for Individuals With Non-specific Chronic Neck Pain: A Randomized Trial.Journal of chiropractic medicine · 2023Article
- Effect Sizes for Changes in Health and Well-Being Following Treatment With the One-To-Zero Technique in Individuals With Occipito-Atlantal Joint Dysfunction: A Repeated Measures Study.Journal of chiropractic medicine · 2023Article
- Article
- Article
- Clinical and Psychological Variables in Female Patients with Cervical Syndromes: A Cross-Sectional and Correlational Study.Healthcare (Basel, Switzerland) · 2022Article
- The Association Between Upper Disorders and Psychological Well-Being and its Implication in Text Neck Syndrome: A Systematic Review.Clinical neuropsychiatry · 2022Review
- Investigation of the effectiveness of neck stabilization exercises in patients with chronic neck pain: A randomized, single-blind clinical, controlled study.Turkish journal of physical medicine and rehabilitation · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough psychosocial factors are known to be highly linked with neck pain, current therapies focus on somatically based interventions such as medicinal or manipulatory therapies. This study examines how socio-demographic, psychosocial and medical history and health-promoting lifestyle factors interact with neck pain in general practice patients.
methodsThis is a cross-sectional survey including 448 patients from a general practice setting in Germany. Participants completed a comprehensive questionnaire including the Neck Pain and Disability Scale German version (NPAD-d) and the Hospital Anxiety and Depression Scale. Crude and adjusted regression analyses were done to assess the relationship between neck pain and socio-demographic, psychosocial and medical history and health-promoting lifestyle factors.
resultsBoth in crude and adjusted regression analyses, depression and anxiety were highly significantly linked with increasing levels of neck pain. Educational level, deficits in social support and physical exercise were associated with neck pain in bivariate analyses, but these associations did not persist with adjustment for depression and anxiety. When investigating levels of depression and anxiety by NPAD-d quartile subgroups, those who were identified to have depressive mood or to be anxious were very likely to be in the group with the highest levels of neck pain.
conclusionThe higher the neck pain level, the more attention should be paid to psychosocial distress as a related burden. Further research is needed to elucidate the causality and the direction of the association between psychosocial distress and neck pain and to determine the benefit of psychosocial interventions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.