Evidence map›Paper›PMID 19168655›Full record

ArticleApplied and environmental microbiology2009

The Salmonella pathogenicity island 2-encoded type III secretion system is essential for the survival of Salmonella enterica serovar Typhimurium in free-living amoebae.

Benjamin Bleasdale, Penelope J Lott, Aparna Jagannathan, Mark P Stevens, Richard J Birtles, Paul Wigley

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Benjamin BleasdaleNational Centre for Zoonosis Research and Department of Veterinary Pathology, University of Liverpool, Leahurst Campus, Neston CH64 7TE, United Kingdom.
Penelope J Lott
Aparna Jagannathan
Mark P Stevens
Richard J Birtles
Paul Wigley
University of Liverpool · GBThe Pirbright Institute · GBNational Consortium for Zoonosis Research · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/00001021
6 · The paper itself

Abstract

Free-living amoebae represent a potential reservoir and predator of Salmonella enterica. Through the use of type III secretion system (T3SS) mutants and analysis of transcription of selected T3SS genes, we demonstrated that the Salmonella pathogenicity island 2 is highly induced during S. enterica serovar Typhimurium infection of Acanthamoeba polyphaga and is essential for survival within amoebae.

Indexed as

Genomic IslandsMicrobial ViabilityAcanthamoebaAnimalsGene Expression ProfilingGenes, BacterialGenes, EssentialMembrane Transport ProteinsMutationSalmonella typhimuriumVirulence FactorsMembrane Transport ProteinsVirulence Factors

Identifiers

PMID19168655
PMCPMC2655480
OpenAlexW2135411083

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.