Evidence map›Paper›PMID 19167433›Full record

ReviewBiochimica et biophysica acta2009

Geometric control of tissue morphogenesis.

Celeste M Nelson

Abstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

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  18. Nets-within-nets for modeling emergent patterns in ontogenetic processes.Computational and structural biotechnology journal · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Celeste M NelsonDepartment of Chemical Engineering, Princeton University, A321 Engineering Quadrangle, Princeton, NJ 08544, USA. celesten@princeton.edu

Funding

Spatial patterning of branching morphogenesisR01GM083997 · NIGMS · PRINCETON UNIVERSITY · PI NELSON, CELESTE M · 2008 to 2012
$1.4M
In Vitro Synthesis of Fibrosis GenesisR21CA128660 · NCI · PRINCETON UNIVERSITY · PI NELSON, CELESTE M · 2007 to 2008
$339k
NCI NIH HHS CA128660NCI NIH HHS R21 CA128660NIGMS NIH HHS GM083997NIGMS NIH HHS R01 GM083997
6 · The paper itself

Abstract

Morphogenesis is the dynamic and regulated change in tissue form that leads to creation of the body plan and development of mature organs. Research over the past several decades has uncovered a multitude of genetic factors required for morphogenesis in animals. The behaviors of individual cells within a developing tissue are determined by combining these genetic signals with information from the surrounding microenvironment. At any point in time, the local microenvironment is influenced by macroscale tissue geometry, which sculpts long range signals by affecting gradients of morphogens and mechanical stresses. The geometry of a tissue thus acts as both a template and instructive cue for further morphogenesis.

Indexed as

AnimalsBody PatterningCell ProliferationCell ShapeIntercellular Signaling Peptides and ProteinsMorphogenesisSignal TransductionStress, MechanicalIntercellular Signaling Peptides and Proteins

Identifiers

PMID19167433
PMCPMC2683193

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.