ArticleNeurocritical care2009
Patterns of increased intracranial pressure after severe traumatic brain injury.
Article in Neurocritical care, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 43 citations in OpenAlex.
- Cerebral Edema in Traumatic Brain Injury.Biomedicines · 2025Review
- Risk factors and predictive model of cerebral edema after road traffic accidents-related traumatic brain injury.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2024Article
- The crisis of the third day in intracranial pressure dynamics following traumatic brain injury, fact or fiction?Brain & spine · 2024Article
- Doxycycline prevents blood-brain barrier dysfunction and microvascular hyperpermeability after traumatic brain injury.Scientific reports · 2022Article
- Glibenclamide Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy.Journal of neurotrauma · 2021Article
- The effect of doxycycline on neuron-specific enolase in patients with traumatic brain injury: a randomized controlled trial.Therapeutic advances in chronic disease · 2021Article
- Can Mesenchymal Stem Cells Act Multipotential in Traumatic Brain Injury?Journal of molecular neuroscience : MN · 2020Review
- Role of Sulfonylurea Receptor 1 and Glibenclamide in Traumatic Brain Injury: A Review of the Evidence.International journal of molecular sciences · 2020Review
- Intracranial pressure dose and outcome in traumatic brain injury.Neurocritical care · 2013Article
- The relationship between basal cisterns on CT and time-linked intracranial pressure in paediatric head injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2011Article
- Aromatase is increased in astrocytes in the presence of elevated pressure.Endocrinology · 2011Article
- Brain herniation in a patient with apparently normal intracranial pressure: a case report.Journal of medical case reports · 2010Article
- The course of intracranial pressure in traumatic brain injury: relation with outcome and CT-characteristics.Neurocritical care · 2010Article
- Intracranial pressure monitoring for traumatic brain injury in the modern era.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2010Review
- Management of intracranial pressure.Current neurology and neuroscience reports · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSecondary brain injury due to increased intracranial pressure (ICP) contributes to post-traumatic morbidity and mortality. Although it is often taught that increased ICP begins early after traumatic brain injury, some patients develop increased ICP after the first 3 days post-injury. We examined our data to describe temporal patterns of increased ICP.
methodsThis is a retrospective review of prospectively collected physiologic and demographic data.
resultsSeventy-seven patients were included. We identified four patterns of increased ICP: beginning within 72 h (early), beginning after 72 h (late), early increases with resolution, and then a second rise after 72 h (bimodal), and continuously increased ICP. Late increases in ICP occur in 17% of this cohort. Peak day of swelling was day 7 for the "late" rise group and day 4 for the other patients with increased ICP. Forty-four percent of patients showed enlargement of cerebral contusions on follow-up imaging at 24 h post-injury.
conclusionsLate rises in ICP were not rare in this cohort. This is clinically relevant as it may impact decisions about ICP monitor removal. Differences between groups in age, CT patterns of injury, fluid therapy, osmotic use, and fever were not statistically significant.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.