Evidence map›Paper›PMID 19165464›Full record

SynthesisIntensive care medicine2009

Depression in general intensive care unit survivors: a systematic review.

Dimitry S Davydow, Jeneen M Gifford, Sanjay V Desai, O Joseph Bienvenu, Dale M Needham

Registry-linked trialOpen access · bronzeAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Intensive care medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04175717 (Is a Physiotherapy-led Follow-up Programme Feasible in Adult Critical Illness Survivors After Discharge Home), which is not on this map. Cited by 201 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
201citing papers in PubMed, 14 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04175717 naterminatednot on this mapstarted 2020, after this paper: background citation

Is a Physiotherapy-led Follow-up Programme Feasible in Adult Critical Illness Survivors After Discharge Home: A Single-center Trial

TypeinterventionalSponsorKantonsspital Winterthur KSWRan2020 to 2020Enrolled3ConditionsPost Intensive Care Unit SyndromeArmsphysiotherapy-led follow-up programme
3 · Its place in the literature

Who cites it

201 citing papers in PubMed, 14 syntheses or guidelines pooled it, 443 citations in OpenAlex.

  1. Pooled it
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  3. [S3 Guideline Sepsis-prevention, diagnosis, therapy, and aftercare : Long version].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2020
    Guideline
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  10. Diaries for recovery from critical illness.The Cochrane database of systematic reviews · 2014
    Pooled it
  11. Guideline
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  14. Pooled it
  15. Trial
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141 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Dimitry S DavydowDepartment of Psychiatry and Behavioral Sciences, Harborview Medical Center, University of Washington School of Medicine, 325 Ninth Avenue, Box 356896, Seattle, WA 98104, USA. ddavydo1@u.washington.edu
Jeneen M Gifford
Sanjay V Desai
O Joseph Bienvenu
Dale M Needham
Johns Hopkins University · USJohns Hopkins Medicine · USMedStar Washington Hospital Center · USUniversity of Washington · US

Funding

VENTILATOR ASSOCIATED LUNG INJURY: MOLECULAR APPROACHESP50HL073994 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI DIETTE, GREGORY B · 2003 to 2007
$21.3M
Personality, anxiety, and depression in community adultsK23MH064543 · NIMH · JOHNS HOPKINS UNIVERSITY · PI BIENVENU, O. JOSEPH · 2003 to 2007
$839k
NHLBI NIH HHS P050 HL73994NHLBI NIH HHS P50 HL073994NIMH NIH HHS K23 MH064543NIMH NIH HHS K23 MH64543
6 · The paper itself

Abstract

purposeTo critically review data on the prevalence of depressive symptoms in general intensive care unit (ICU) survivors, risk factors for these symptoms, and their impact on health-related quality of life (HRQOL).

methodsWe conducted a systematic review using Medline, EMBASE, Cochrane Library, CINAHL, PsycINFO, and a hand-search of 13 journals.

resultsFourteen studies were eligible. The median point prevalence of "clinically significant" depressive symptoms was 28% (total n = 1,213). Neither sex nor age were consistent risk factors for post-ICU depression, and severity of illness at ICU admission was consistently not a risk factor. Early post-ICU depressive symptoms were a strong risk factor for subsequent depressive symptoms. Post-ICU depressive symptoms were associated with substantially lower HRQOL.

conclusionsDepressive symptoms are common in general ICU survivors and negatively impact HRQOL. Future studies should address how factors related to individual patients, critical illness and post-ICU recovery are associated with depression in ICU survivors.

Indexed as

Critical IllnessHealth StatusHospitalizationHumansIntensive Care UnitsMajor Depressive DisorderQuality of LifeSurvivors

Identifiers

PMID19165464
PMCPMC10885708
OpenAlexW2042278366

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.