ArticleEuropean heart journal2009
Metabolic syndrome and collateral vessel formation in patients with documented occluded coronary arteries: association with hyperglycaemia, insulin-resistance, adiponectin and plasminogen activator inhibitor-1.
Article in European heart journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 78 citations in OpenAlex.
- Double-blinded, randomized clinical trial of Gegen Qinlian decoction pinpointsPrecision clinical medicine · 2024Trial
- The association between single-point insulin sensitivity estimator and high-sensitivity C-reactive protein with collateral circulation in coronary chronic total occlusion.Frontiers in endocrinology · 2026Article
- Association between the atherogenic index of plasma and coronary collateral circulation in patients with chronic total occlusion.BMC cardiovascular disorders · 2024Article
- [Correlation between insulin resistance and coronary collateral circulation in patients with chronic total coronary occlusion].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- Correlation between triglyceride glucose index and collateral circulation formation in patients with chronic total occlusion of coronary arteries in different glucose metabolic states.Cardiovascular diabetology · 2024Article
- Impact of coronary collateralization on major adverse cardiovascular and cerebrovascular events after successful recanalization of chronic total occlusion.Frontiers in cardiovascular medicine · 2024Article
- Impacts of Non-alcoholic Fatty Liver Disease on Acute Coronary Syndrome: Evidence and Controversies.Current atherosclerosis reports · 2023Review
- The predictive value of the triglyceride-glucose index for cardiovascular events in patients with coronary chronic total occlusion.Cardiovascular diabetology · 2022Article
- The essential role for endothelial cell sprouting in coronary collateral growth.Journal of molecular and cellular cardiology · 2022Article
- Isolated systolic hypertension and insulin resistance assessment tools in young and middle-aged Chinese men with normal fasting glucose: a cross-sectional study.Scientific reports · 2022Article
- Association between the triglyceride glucose index and coronary collateralization in coronary artery disease patients with chronic total occlusion lesions.Lipids in health and disease · 2021Observational
- Metabolic syndrome and its components reduce coronary collateralization in chronic total occlusion: An observational study.Cardiovascular diabetology · 2021Observational
- Traditional Cardiovascular Risk Factors and Coronary Collateral Circulation: A Meta-Analysis.Frontiers in cardiovascular medicine · 2021Article
- Differences of Angiogenesis Factors in Tumor and Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Review
- Visceral fat index: a novel predictor for coronary collateral circulation.Archives of endocrinology and metabolism · 2020Article
- Plasma Omentin-1 Level as a Predictor of Good Coronary Collateral Circulation.Journal of atherosclerosis and thrombosis · 2017Article
- Cardiovascular function in male and female JCR:LA-cp rats: effect of high-fat/high-sucrose diet.American journal of physiology. Heart and circulatory physiology · 2017Article
- Elevated 20-HETE impairs coronary collateral growth in metabolic syndrome via endothelial dysfunction.American journal of physiology. Heart and circulatory physiology · 2017Article
- Endurance, interval sprint, and resistance exercise training: impact on microvascular dysfunction in type 2 diabetes.American journal of physiology. Heart and circulatory physiology · 2016Review
- Mechanisms of Comorbidities Associated With the Metabolic Syndrome: Insights from theFrontiers in nutrition · 2016Review
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe metabolic syndrome (MS) is associated with an increased cardiovascular risk. Patients with the MS have endothelial dysfunction, decreased circulating adiponectin, and a high expression of angiogenic inhibitors such as plasminogen activator inhibitor-1 (PAI-1). We hypothesized that such patients, in the event of a coronary occlusion, might exhibit a less developed collateral circulation. METHODS AND
resultsThree hundred and eighty-seven consecutive patients with at least one coronary occlusion of a major coronary vessel at diagnostic angiography were prospectively enrolled. Collateral development was graded with validated angiographic methods. The MS was defined according to the ATP-III definition. Fasting glucose, adiponectin, insulin concentrations, and PAI-1 were measured at the time of angiography. MS was associated with less developed collateral vessels (P = 0.005). In multivariable analysis adjusting for potential confounding factors including the duration of coronary occlusion (P = 0.0001), fasting glycaemia (P = 0.0007), low adiponectin concentration (P = 0.01), insulin-resistance (HOMA-IR; P = 0.01), high circulating PAI-1 concentration (P = 0.01), and hypertension (P = 0.008) were independently associated with poor coronary collateral vessel development.
conclusionThis study shows that in patients with coronary occlusion, collateral circulation is impaired in patients with the MS. This association is partly related to fasting glycaemia and to key parameters linked to insulin resistance.
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