ArticleMicrobial pathogenesis2009
Transcript analysis of nrrF, a Fur repressed sRNA of Neisseria gonorrhoeae.
Article in Microbial pathogenesis, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 38 citations in OpenAlex.
- Complex interplay of riboregulatory mechanisms at theJournal of bacteriology · 2026Article
- Transcriptional activation ofmBio · 2023Article
- Molecular Regulatory Mechanisms Drive Emergent Pathogenetic Properties ofMicroorganisms · 2022Review
- Impacts of Small RNAs and Their Chaperones on Bacterial Pathogenicity.Frontiers in cellular and infection microbiology · 2021Review
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- Article
- Bacterial Iron Homeostasis Regulation by sRNAs.Microbiology spectrum · 2018Review
- Iron-regulated small RNA expression as Neisseria gonorrhoeae FA 1090 transitions into stationary phase growth.BMC genomics · 2017Article
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- Characterization of the Neisseria gonorrhoeae Iron and Fur Regulatory Network.Journal of bacteriology · 2016Article
- Article
- Identification of sRNAs expressed by the human pathogen Neisseria gonorrhoeae under disparate growth conditions.Frontiers in microbiology · 2014Article
- Phase variation in Myxococcus xanthus yields cells specialized for iron sequestration.PloS one · 2014Article
- Transcriptional landscape and essential genes of Neisseria gonorrhoeae.Nucleic acids research · 2014Article
- Article
- Control of RNA stability by NrrF, an iron-regulated small RNA in Neisseria gonorrhoeae.Journal of bacteriology · 2013Article
- Iron-responsive bacterial small RNAs: variations on a theme.Metallomics : integrated biometal science · 2013Review
- Iron homeostasis in theAdvances in botanical research · 2013Article
- Transcriptional regulation by Ferric Uptake Regulator (Fur) in pathogenic bacteria.Frontiers in cellular and infection microbiology · 2013Review
- Fur-mediated global regulatory circuits in pathogenic Neisseria species.Journal of bacteriology · 2012Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Like most microorganisms, Neisseria gonorrhoeae alters gene expression in response to iron availability. The ferric uptake regulator Fur has been shown to be involved in controlling this response, but the extent of this involvement remains unknown. It is known that in addition to working directly to repress gene expression, Fur may also work indirectly by controlling additional regulatory elements. Using in silico analysis, we identified a putative small RNA (sRNA) homolog of the meningococcal nrrF locus, and demonstrate that this sRNA is iron-repressible, suggesting that this is the gonococcal analog of the rhyB locus in Escherichia coli. Quantitative real-time RT-PCR analysis indicates that this transcript may also be temporally regulated. Transcript analysis identified the 5' start of the transcript, using a single reaction, fluorescent-based, primer extension assay. This protocol allows for the rapid identification of transcriptional start sites of RNA transcripts, and could be used for high-throughput transcript mapping.
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Registered trials
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