ReviewClinics in perinatology2009
Anemia in the preterm infant: erythropoietin versus erythrocyte transfusion--it's not that simple.
Review in Clinics in perinatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 46 citations in OpenAlex.
- Darbepoetin and Infantile Hemangioma in Premature Infants.Journal of clinical medicine · 2026Article
- Development of an electrochemiluminescence assay to measure serum darbepoetin concentration in extremely preterm infants.Bioanalysis · 2025Article
- The Role of Erythropoietin in Preventing Anemia in the Premature Neonate.Children (Basel, Switzerland) · 2023Article
- Risk factors for anemia of prematurity among 30-35-week preterm infants.Fukushima journal of medical science · 2023Article
- Predictors of adverse short-term outcomes in late preterm infants.BMC pediatrics · 2023Article
- Characterization of Neutropenia in Preterm Neonates Following Administration of Darbepoetin Alfa.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023Article
- Evaluation of vitamin DScientific reports · 2019Article
- A Mechanism-Based Population Pharmacokinetics Model of Erythropoietin in Premature Infants and Healthy Adults Following Multiple Intravenous Doses.Journal of clinical pharmacology · 2019Article
- Association between anemia and bronchopulmonary dysplasia in preterm infants.Scientific reports · 2016Observational
- Transfusion related morbidity in premature babies: Possible mechanisms and implications for practice.World journal of clinical pediatrics · 2014Review
- Predictors of fetal anemia and cord blood malaria parasitemia among newborns of HIV-positive mothers.BMC research notes · 2013Article
- Association of necrotizing enterocolitis with anemia and packed red blood cell transfusions in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Since the late 1980s recombinant human erythropoietin (r-EPO) has been studied as an alternative to packed red blood cell (RBC) transfusion for the treatment of anemia of prematurity in very low birth weight infants. Initial trials and reports focused on r-EPO's ability to prevent or treat anemia of prematurity with the goal of eliminating RBC transfusion but achieved limited success. New concerns about the safety of r-EPO administration have emerged. Past cost-benefit analyses of r-EPO administration versus transfusion for the treatment of anemia of prematurity have been nearly balanced. Autologous transfusion, blood-sparing technologies, changes in RBC transfusion technique and safety, and further elucidation of the risk-benefit ratio of r-EPO therapy may change the cost-benefit analysis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.