ArticleClinics in perinatology2009
Drugs of choice for sedation and analgesia in the neonatal ICU.
Article in Clinics in perinatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Analgesia for retinopathy of prematurity screening: A systematic review.Pain practice : the official journal of World Institute of Pain · 2022Pooled it
- Paracetamol (acetaminophen) use in infants and children was never shown to be safe for neurodevelopment: a systematic review with citation tracking.European journal of pediatrics · 2022Pooled it
- Acetaminophen (Paracetamol) Induces Hypothermia During Acute Cold Stress.Clinical drug investigation · 2017Trial
- Fentanyl Exposure Is Associated with Adverse Respiratory Outcomes in Ventilated Preterm Neonates: A Retrospective Matched Cohort Study.Journal of clinical medicine · 2026Article
- Analgesia and sedation trends in a level IV NICU, 2014-2024: Opioid and dexmedetomidine use.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- The Effects of Music on Inflammation: A Bibliometric Study from 1989 to 2024.Journal of inflammation research · 2026Review
- Investigating the neurobiology of maternal opioid use disorder and prenatal opioid exposure using brain organoid technology.Frontiers in cellular neuroscience · 2024Review
- Transfontanelle photoacoustic imaging of intraventricular brain hemorrhages in live sheep.Photoacoustics · 2023Article
- Development and characterization of transfontanelle photoacoustic imaging system for detection of intracranial hemorrhages and measurement of brain oxygenation:Photoacoustics · 2023Article
- A ketamine package for use in emergency cesarean delivery when no anesthetist is available: An analysis of 401 consecutive operations.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022Article
- Long-Lasting Analgesia With Transdermal Fentanyl: A New Approach in Rat Neonatal Research.Frontiers in pharmacology · 2022Article
- Future roles of artificial intelligence in early pain management of newborns.Paediatric & neonatal pain · 2021Review
- Differential effects of four intramuscular sedatives on cardiorespiratory stability in juvenile guinea pigs (Cavia porcellus).PloS one · 2021Article
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- The effect of levomepromazine on the healthy and injured developing mouse brain - AnIBRO reports · 2020Article
- First-Pass CYP3A-Mediated Metabolism of Midazolam in the Gut Wall and Liver in Preterm Neonates.CPT: pharmacometrics & systems pharmacology · 2018Article
- Ketamine-induced neuroapoptosis in the fetal and neonatal rhesus macaque brain.Anesthesiology · 2012Article
- Post-discharge healthcare utilization in infants with neonatal opioid withdrawal syndrome.Neurotoxicology and teratologyArticle
Corrections and comments
- Erratum issuedDosage error in article text
- Republished as
Authors and funding
2 authors.
Funding
Abstract
Painful procedures in the neonatal ICU are common, undertreated, and lead to adverse consequences. The drugs most commonly used to treat neonatal pain include the opiates, benzodiazepines, barbiturates, ketamine, propofol, acetaminophen, and local and topical anesthetics. This article discusses the indications for and advantages and disadvantages of the commonly used analgesic drugs. Guidance and references for drugs and dosing for specific neonatal procedures are provided.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.