SynthesisThe Cochrane database of systematic reviews2009
Cholecystectomy for gallbladder polyp.
Synthesis in The Cochrane database of systematic reviews, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Risk of developing gallbladder cancer in patients with gallbladder polyps detected on transabdominal ultrasound: a systematic review and meta-analysis.The British journal of radiology · 2022Pooled it
- Diagnostic accuracy of transabdominal ultrasonography for gallbladder polyps: systematic review.Canadian journal of surgery. Journal canadien de chirurgie · 2018Pooled it
- Gallbladder cancer: expert consensus statement.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2015Guideline
- SAGES guidelines for the clinical application of laparoscopic biliary tract surgery.Surgical endoscopy · 2010Guideline
- Role of Endoscopy in Management of Upper Gastrointestinal Cancers.Diseases (Basel, Switzerland) · 2022Review
- Bile cholesterol and viscosity, the keys to discriminating adenomatous polyps from cholesterol polyps by a novel predictive scoring model.BMC gastroenterology · 2020Article
- Abdominal pain and vomiting during pregnancy due to cholesterolosis.BMJ case reports · 2019Article
- Current practices and future prospects for the management of gallbladder polyps: A topical review.World journal of gastroenterology · 2018Review
- Laparoscopic cholecystectomy: consensus conference-based guidelines.Langenbeck's archives of surgery · 2015Review
- Is cholecystectomy a reasonable treatment option for simple gallbladder polyps larger than 10 mm?World journal of gastroenterology · 2015Article
- Renal cell carcinoma metastases to gallbladder.Annals of the Royal College of Surgeons of England · 2013Article
- Treatment and surveillance of polypoid lesions of the gallbladder in the United Kingdom.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe management of gallbladder polyps is controversial. Cholecystectomy has been recommended for gallbladder polyps larger than 10 mm because of the association with gallbladder cancer. Cholecystectomy has also been suggested for gallbladder polyps smaller than 10 mm in patients with biliary type of symptoms.
objectivesThe aim of this review is to compare the benefits (relief of symptoms, decreased incidence of gallbladder cancer) and harms (surgical morbidity) of cholecystectomy in patients with gallbladder polyp(s). SEARCH STRATEGY: We searched The Cochrane Hepato-Biliary Group Controlled Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, MEDLINE, EMBASE, and Science Citation Index Expanded until July 2008 to identify the randomised trials. SELECTION CRITERIA: Only randomised clinical trials (irrespective of language, blinding, or publication status) comparing cholecystectomy and no cholecystectomy were considered for the review. DATA COLLECTION AND ANALYSIS: We planned to collect the data on the characteristics, methodological quality, mortality, number of patients in whom symptoms were improved or cured from the one identified trial. We planned to analyse the data using the fixed-effect and the random-effects models using RevMan Analysis. For each outcome we planned to calculate the risk ratio (RR) with 95% confidence intervals based on intention-to-treat analysis. MAIN
resultsWe were unable to identify any randomised clinical trials comparing cholecystectomy versus no cholecystectomy in patients with a gallbladder polyp. AUTHORS'
conclusionsThere are no randomised trials comparing cholecystectomy versus no cholecystectomy in patients with gallbladder polyps. Randomised clinical trials with low bias -risk are necessary to address the question of whether cholecystectomy is indicated in gallbladder polyps smaller than10 mm.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.