ArticleBMC genomics2009
Positive correlation between gene coexpression and positional clustering in the zebrafish genome.
Article in BMC genomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
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- The clustering of functionally related genes contributes to CNV-mediated disease.Genome research · 2015Article
- Transcriptomics of salinity tolerance capacity in Arctic charr (Salvelinus alpinus): a comparison of gene expression profiles between divergent QTL genotypes.Physiological genomics · 2014Article
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- The duplicated genes database: identification and functional annotation of co-localised duplicated genes across genomes.PloS one · 2012Article
- Nonlinear dependence in the discovery of differentially expressed genes.ISRN bioinformatics · 2012Article
- Arm-specific dynamics of chromosome evolution in malaria mosquitoes.BMC evolutionary biology · 2011Article
- Whole-genome expression plasticity across tropical and temperate Drosophila melanogaster populations from Eastern Australia.Molecular biology and evolution · 2011Article
- Support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation.Genome biology · 2011Article
- Clock genes and their genomic distributions in three species of salmonid fishes: Associations with genes regulating sexual maturation and cell cycling.BMC research notes · 2010Article
- Gene Expression in the Three-Spined Stickleback (Gasterosteus aculeatus) of Marine and Freshwater Ecotypes.Acta naturaeArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCo-expressing genes tend to cluster in eukaryotic genomes. This paper analyzes correlation between the proximity of eukaryotic genes and their transcriptional expression pattern in the zebrafish (Danio rerio) genome using available microarray data and gene annotation.
resultsThe analyses show that neighbouring genes are significantly coexpressed in the zebrafish genome, and the coexpression level is influenced by the intergenic distance and transcription orientation. This fact is further supported by examining the coexpression level of genes within positional clusters in the neighbourhood model. There is a positive correlation between gene coexpression and positional clustering in the zebrafish genome.
conclusionThe study provides another piece of evidence for the hypothesis that coexpressed genes do cluster in the eukaryotic genomes.
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