ReviewClinical genetics2009
Noncoding RNAs in mental retardation.
Review in Clinical genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- Integrative analyses of genes and microRNA expressions in human trisomy 21 placentas.BMC medical genomics · 2018Article
- MicroRNA Expression Profile in the Prenatal Amniotic Fluid Samples of Pregnant Women with Down Syndrome.Balkan medical journal · 2018Article
- Decreased miRNA expression in Klinefelter syndrome.Scientific reports · 2017Article
- MicroRNAs as potential biomarkers for noninvasive detection of fetal trisomy 21.Journal of assisted reproduction and genetics · 2015Article
- miRNA and miRNA target genes in copy number variations occurring in individuals with intellectual disability.BMC genomics · 2013Article
- Genomic and clinical characteristics of six patients with partially overlapping interstitial deletions at 10p12p11.European journal of human genetics : EJHG · 2011Article
- The role of microRNAs in the biology of rare diseases.International journal of molecular sciences · 2011Review
- Do different neurons age differently? Direct genome-wide analysis of aging in single identified cholinergic neurons.Frontiers in aging neuroscience · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Recent genome-wide interrogations of transcribed RNA have yielded compelling evidence for pervasive and complex transcription throughout a large majority of the human genome. Tens of thousands of noncoding RNA transcripts have been identified, most of which have yet to be functionally characterized. Along with the revelation that noncoding RNAs in the human genome are surprisingly abundant, there has been a surge in molecular and genetic data showing important and diverse regulatory roles for noncoding RNA. In this report, we summarize the potential roles that noncoding RNAs may play in the molecular pathogenesis of different mental retardation disorders. We suspect that these findings are just the tip of the iceberg, with noncoding RNAs possibly being involved in disease pathogenesis at different levels and through multiple distinct mechanisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.