Evidence map›Paper›PMID 19158939›Full record

ArticleFood & nutrition research2008

Physical activity, muscle function, falls and fractures.

Magnus K Karlsson, Anders Nordqvist, Caroline Karlsson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food & nutrition research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 78 citations in OpenAlex.

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  3. Effects of exercise on fracture reduction in older adults: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013
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  17. The associations of physical activity with fracture risk--a 7-year prospective controlled intervention study in 3534 children.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Magnus K KarlssonDepartment of Orthopaedics and Clinical and Molecular Osteoporosis Research Unit, Department of Clinical Sciences, Malmö University Hospital, Lund University, Sweden.
Anders Nordqvist
Caroline Karlsson
Lund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designA thematic review.

objectivesTo evaluate if physical activity enhances muscle strength, improves balance, and reduces the fall frequency and the fracture incidence.

backgroundOne of the major medical problems of today is the increasing incidence of fragility fractures. Muscle strength and fall is one of the major determinants of a fracture. If physical activity could increase muscle strength, improve balance and reduce the fall frequency, then training could be recommended as prevention for fractures.

methodsThe review used Medline (Pub Med) and the search words exercise, physical activity, muscle strength, balance, falls, fractures. Randomized controlled trials (RCT) were predominantly included, although this not is a systematic review.

resultsThe evidence that physical activity modifies the risk factors for fall is compelling, although RCT with fractures as end point are lacking. Physical activity is associated with improved muscle strength, co-ordination and balance. Physical training increases muscle strength also in octogenarians by up to 200%, i.e. a much more pronounced effect than the corresponding increase in muscle volume or bone mass. There is also evidence that physical activity decreases the actual number of falls. Observational cohort and case-control studies imply that physical activity is associated with reduced hip fracture risk. If exercise reduces the number of vertebral fractures and other fragility fractures are less evaluated.

conclusionsPhysical activity in older ages can be recommended to improve muscle strength and balance, to reduce the risk to fall and fractures, although the highest level of evidence - RCT with fracture as endpoint - is lacking.

Indexed as

exercisefallfracturesmuscle massmuscle strengthphysical activity

Identifiers

PMID19158939
PMCPMC2615636
OpenAlexW2121200189

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.