ArticleInternational journal of clinical and experimental pathology2009
Mammaglobin, a valuable diagnostic marker for metastatic breast carcinoma.
Article in International journal of clinical and experimental pathology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 54 citations in OpenAlex.
- Mammaglobin-A immunohistochemistry in primary central nervous system neoplasms and intracranial metastatic breast carcinoma.Applied immunohistochemistry & molecular morphology : AIMM · 2014Trial
- Gastric and peritoneal metastases from breast carcinoma with a mixed ductal-lobular phenotype and aberrant E-cadherin: a case report.Journal of surgical case reports · 2026Article
- Circulating tumor cells (CTCs) enumeration and machine-learning based diagnostic biomarkers for breast cancer detection.BMC cancer · 2026Article
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- The Enigma of Mammaglobin: Redefining the Biomarker Paradigm in Breast Carcinoma.International journal of molecular sciences · 2023Review
- Comparison of microfluidic platforms for the enrichment of circulating tumor cells in breast cancer patients.Breast cancer research and treatment · 2022Article
- Peptide-Based Vaccines in Clinical Phases and New Potential Therapeutic Targets as a New Approach for Breast Cancer: A Review.Vaccines · 2022Review
- Intestinal metastasis from breast cancer: Presentation, treatment and survival from a systematic literature review.World journal of clinical oncology · 2021Article
- Bone marrow mammaglobin-1 (SCGB2A2) immunohistochemistry expression as a breast cancer specific marker for early detection of bone marrow micrometastases.Scientific reports · 2020Article
- Gastric and adrenal metastasis from breast cancer: Case report and review of literature.Medicine · 2020Review
- Detection of human mammaglobin mRNA in breast cancer cells among Vietnamese women.Breast cancer (Dove Medical Press) · 2019Article
- Over-expression of mammaglobin-B in canine mammary tumors.BMC veterinary research · 2018Article
- Immunohistochemical Analysis of the Expression of Breast Markers in Basal-like Breast Carcinomas Defined as Triple Negative Cancers Expressing Keratin 5.Pathology oncology research : POR · 2018Article
- Preferential expression of NY-BR-1 and GATA-3 in male breast cancer.Journal of cancer research and clinical oncology · 2018Article
- Prognostic role of plasma mammaglobin A expression in breast carcinoma patients: a meta-analysis.OncoTargets and therapy · 2018Review
- Repeated changes of the molecular subtype in gastric metastasis from breast cancer: A case report.Molecular and clinical oncology · 2016Article
- Generation of monoclonal antibodies against MGA and comparison of their application in breast cancer detection by immunohistochemistry.Scientific reports · 2015Article
- Safety and preliminary evidence of biologic efficacy of a mammaglobin-a DNA vaccine in patients with stable metastatic breast cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2014Article
- Human mammaglobin in breast cancer: a brief review of its clinical utility.The Indian journal of medical research · 2014Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Identification of metastasis and occult micrometastases of breast cancer demands sensitive and specific diagnostic markers. In this study, we assessed the utility of a mouse monoclonal antibody to human mammaglobin for one such purpose. Immunohistochemical stains were performed on paraffin-embedded sections from a total of 284 cases, which consisted of primary breast invasive carcinomas (41 cases) with matched metastases to ipsilateral axillary lymph nodes, metastatic breast carcinoma to liver (1 case) and kidney (1 case), non-breast neoplasms (161 cases), and normal human tissues (39 cases). The results showed 31 of the 41 cases of primary breast cancer with axillary lymph node metastases were positive for mammaglobin (76%). In the meantime, we documented expression of mammaglobin in occasional cases of endometrial carcinoma (17%). Our data further validated that mammaglobin is a valuable diagnostic marker for metastatic carcinoma of breast origin, although endometrial carcinoma should be considered as a major differential diagnosis.
Indexed as
Identifiers
19158935PMC2615595W171742669What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.