Evidence map›Paper›PMID 19158603›Full record

ReviewJournal of investigative medicine : the official publication of the American Federation for Clinical Research2009

Designer natriuretic peptides.

Candace Y W Lee, Hsiao Lieu, John C Burnett

Open access · greenAbstract readReview
In one paragraph

Review in Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Novel drug mechanisms in development for heart failure.Pflugers Archiv : European journal of physiology · 2014
    Review
  6. Evolving treatment strategies for management of cardiorenal syndrome.Current treatment options in cardiovascular medicine · 2011
    Article
  7. Review
  8. Review
  9. Progress toward genetic tailoring of heart failure therapy.Current opinion in molecular therapeutics · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Candace Y W LeeDepartments of Internal Medicine and Physiology, Division of Cardiovascular Disease, Cardiorenal Research Laboratory, Mayo Clinic College of Medicine, Rochester, MN 55906, USA.
Hsiao Lieu
John C Burnett
Mayo Clinic · US

Funding

Recruitment and Phenotyping CoreP01HL076611 · NHLBI · MAYO CLINIC ROCHESTER · PI BURNETT, JOHN C · 2005 to 2015
$19.6M
INTRARENAL REGULATION OF SODIUM EXCRETIONR01HL036634 · NHLBI · MAYO CLINIC ROCHESTER · PI BURNETT, JOHN C · 1987 to 2019
$6.5M
Cardiovascular Peptides and Myocardial InfarctionR01HL083231 · NHLBI · MAYO CLINIC ROCHESTER · PI BURNETT, JOHN C, CHEN, HORNG H · 2006 to 2016
$4.6M
AFMR-Translational Medical Research Symposia SeriesR13RR023236 · NCRR · AMERICAN FEDERATION FOR MEDICAL RESEARCH · PI ZUCKER, DEBORAH R · 2006 to 2010
$263k
NCRR NIH HHS R13 RR023236NHLBI NIH HHS P01 HL076611NHLBI NIH HHS P01 HL6611NHLBI NIH HHS R01 HL036634NHLBI NIH HHS R01 HL083231NHLBI NIH HHS R01 HL36634NHLBI NIH HHS R01 HL83231
6 · The paper itself

Abstract

Designer natriuretic peptides (NPs) are novel hybrid peptides that are engineered from the native NPs through addition, deletion, or substitution of amino acid(s) with a goal toward optimization of pharmacological actions while minimizing undesirable effects. In this article, selected peptides that were designed in our laboratory are reviewed, and future directions for research and development of designer NPs are discussed.

Indexed as

Drug DesignNatriuretic PeptidesHumansNatriuretic Peptides

Identifiers

PMID19158603
PMCPMC3129707
OpenAlexW2173818307

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.