ArticleProteins2009
Dissection of the critical binding determinants of cellular retinoic acid binding protein II by mutagenesis and fluorescence binding assay.
Article in Proteins, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 14 citations in OpenAlex.
- Photoisomerization detected in a fully wavelength-tunable rhodopsin mimic system.Acta crystallographica. Section D, Structural biology · 2026Article
- Structure-functional relationship of cellular retinoic acid-binding proteins I and II interacting with natural and synthetic ligands.Acta crystallographica. Section D, Structural biology · 2021Article
- Human Cellular Retinol Binding Protein II Forms a Domain-Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering.Chembiochem : a European journal of chemical biology · 2020Article
- Engineering of a Red Fluorogenic Protein/Merocyanine Complex for Live-Cell Imaging.Chembiochem : a European journal of chemical biology · 2020Article
- Probing biological activity through structural modelling of ligand-receptor interactions of 2,4-disubstituted thiazole retinoids.Bioorganic & medicinal chemistry · 2018Article
- The molecular basis of the interactions between synthetic retinoic acid analogues and the retinoic acid receptors.MedChemComm · 2017Article
- Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates.Structure (London, England : 1993) · 2016Article
- A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution.Journal of the American Chemical Society · 2016Article
- Light-Activated Reversible Imine Isomerization: Towards a Photochromic Protein Switch.Chembiochem : a European journal of chemical biology · 2016Article
- Article
- Rational design of a colorimetric pH sensor from a soluble retinoic acid chaperone.Journal of the American Chemical Society · 2013Article
- Elucidating the exact role of engineered CRABPII residues for the formation of a retinal protonated Schiff base.Proteins · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
The binding of retinoic acid to mutants of Cellular Retinoic Acid Binding Protein II (CRABPII) was evaluated to better understand the importance of the direct protein/ligand interactions. The important role of Arg111 for the correct structure and function of the protein was verified and other residues that directly affect retinoic acid binding have been identified. Furthermore, retinoic acid binding to CRABPII mutants that lack all previously identified interacting amino acids was rescued by providing a carboxylic acid dimer partner in the form of a Glu residue.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.