ReviewEuropean journal of nuclear medicine and molecular imaging2009
Nuclear imaging in cardiac amyloidosis.
Review in European journal of nuclear medicine and molecular imaging, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 94 citations in OpenAlex.
- Usefulness and limitations of 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy in the aetiological diagnosis of amyloidotic cardiomyopathy.European journal of nuclear medicine and molecular imaging · 2011Trial
- Novel Insights into Non-Invasive Diagnostic Techniques for Cardiac Amyloidosis: A Critical Review.Diagnostics (Basel, Switzerland) · 2024Review
- Value of nuclide scintigraphy in the diagnosis and prognosis of cardiac amyloidosis.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023Article
- Quantitative SPECT/CT Parameters in the Assessment of Transthyretin Cardiac Amyloidosis-A New Dimension of Molecular Imaging.Journal of cardiovascular development and disease · 2023Review
- Deep-learning-based cardiac amyloidosis classification from early acquired pet images.The international journal of cardiovascular imaging · 2021Article
- Application-specific nuclear medicalPhysics in medicine and biology · 2021Review
- Diagnostic challenges in systemic amyloidosis: a case report with clinical and laboratorial pitfalls.Autopsy & case reports · 2021Article
- Clinical and Research Tools for the Study of Cardiovascular Effects of Cancer Therapy.Journal of cardiovascular translational research · 2020Review
- 99mTc-DPD scintigraphy and SPECT/CT in patients with AL and ATTR type amyloidosis: Potential clinical implications.Medicine · 2020Observational
- Molecular Imaging of Cardiac Amyloidosis.Current cardiology reports · 2019Review
- Isolated cardiac amyloidosis. Utility of bone seeking tracers scintigraphy in differentiating the subtype of amyloid: A case report.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- The role of nuclear cardiac imaging in risk stratification of sudden cardiac death.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Accurate analysis and visualization of cardiac (11)C-PIB uptake in amyloidosis with semiautomatic software.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Imaging Findings and Literature Review of (18)F-FDG PET/CT in Primary Systemic AL Amyloidosis.Nuclear medicine and molecular imaging · 2015Article
- Role of imaging in the diagnosis and management of patients with cardiac amyloidosis: state of the art review and focus on emerging nuclear techniques.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Review
- Nuclear imaging of amyloidosis.Polish journal of radiology · 2014Review
- Cardiac sarcoidosis: case report, workup, and review of the literature.Cardiology and therapy · 2013Article
- Guideline of transthyretin-related hereditary amyloidosis for clinicians.Orphanet journal of rare diseases · 2013Review
- Re-evaluating the potentials and limitations of (99m)Tc-aprotinin scintigraphy for amyloid imaging.American journal of nuclear medicine and molecular imaging · 2013Article
- A binding-site barrier affects imaging efficiency of high affinity amyloid-reactive peptide radiotracers in vivo.PloS one · 2013Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amyloidosis is a disease characterized by depositions of amyloid in organs and tissues. It can be localized (in just one organ) or systemic. Cardiac amyloidosis is a debilitating disease and can lead to arrhythmias, deterioration of heart function and even sudden death. We reviewed PubMed/Medline, without time constraints, on the different nuclear imaging modalities that are used to visualize myocardial amyloid involvement. Several SPECT tracers have been used for this purpose. The results with these tracers in the evaluation of myocardial amyloidosis and their mechanisms of action are described. Most clinical evidence was found for the use of (123)I-MIBG. Myocardial defects in MIBG activity seem to correlate well with impaired cardiac sympathetic nerve endings due to amyloid deposits. (123)I-MIBG is an attractive option for objective evaluation of cardiac sympathetic level and may play an important role in the indirect measurement of the effect of amyloid myocardial infiltration. Other, less sensitive, options are (99m)Tc-aprotinin for imaging amyloid deposits and perhaps (99m)Tc-labelled phosphate derivatives, especially in the differential diagnosis of the aetiology of cardiac amyloidosis. PET tracers, despite the advantage of absolute quantification and higher resolution, are not yet well evaluated for the study of cardiac amyloidosis. Because of these advantages, there is still the need for further research in this field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.