Evidence map›Paper›PMID 19156235›Full record

ReviewTexas Heart Institute journal2008

Retractable-needle catheters: an update on local drug delivery in coronary interventions.

Paolo Angelini, Wijay Bandula

Open access · greenAbstract readReview
In one paragraph

Review in Texas Heart Institute journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Paolo AngeliniDepartment of Cardiology, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas 77030, USA. pangelini@leachmancardiology.com
Wijay Bandula
St. Luke's Episcopal Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the treatment of coronary artery disease, local delivery of pharmaceutical substances has long been a goal, yet the technology is still evolving. Coronary stents have become the predominant means of treating obstructive lesions, and the need for additional pharmacologic treatment is evidenced by the popularity of drug-eluting stents. Moreover, stents have residual limitations, in particular in-stent thrombosis and late restenosis. Investigators have recently proposed delivering coronary drugs by means of local injection devices. These innovative devices, which incorporate retractable needles at the tip of a catheter, appear to be ready for clinical testing. In addition to solving many of the limitations of drug-eluting stents, local injection devices may eventually enable interventional cardiologists to treat vulnerable plaques. Herein, we review the evolution and current status of local drug delivery in the coronary arteries, with an emphasis on novel catheters that have retractable needles.

Indexed as

Drug-Eluting StentsCatheterization, PeripheralCoronary AngiographyCoronary Artery DiseaseCoronary RestenosisDelayed-Action PreparationsDrug Delivery SystemsDrug ImplantsHumansInjections, IntralesionalNeedlesDelayed-Action PreparationsDrug ImplantsCardiovascular agents/therapeutic usecoronary artery disease/economicscoronary disease/drug therapycoronary restenosis/prevention & control/therapycoronary stenosis/complicationsdelayed-action preparations/administration & dosagedrug delivery systems/instrumentation/methodsdrug implantsequipment designstents/adverse effects

Identifiers

PMID19156235
PMCPMC2607095
OpenAlexW32077860

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.