ArticleEvolution; international journal of organic evolution2009
Reversing mother's curse: selection on male mitochondrial fitness effects.
Article in Evolution; international journal of organic evolution, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 82 citations in OpenAlex.
- Absence of Mother's Curse for performance traits among divergent mtDNAs in heterozygous nuclear backgrounds in Drosophila.bioRxiv : the preprint server for biology · 2025Article
- Testing the Mother's Curse Hypothesis in Human Mitochondrial Genome Evolution.Genome biology and evolution · 2025Article
- Support for Y-compensation of mother's curse affecting lifespan in Drosophila melanogaster.Heredity · 2024Article
- Mother's Curse effects on lifespan and aging.Frontiers in aging · 2024Review
- Mitochondrial effects on fertility and longevity inProceedings. Biological sciences · 2022Article
- Investigating the Impact of a Curse: Diseases, Population Isolation, Evolution and the Mother's Curse.Genes · 2022Review
- Migration restores hybrid incompatibility driven by mitochondrial-nuclear sexual conflict.Proceedings. Biological sciences · 2022Article
- Sex-biased demography modulates male harm across the genome.Proceedings. Biological sciences · 2021Article
- Adaptive co-evolution of mitochondria and the Y-chromosome: A resolution to conflict between evolutionary opponents.Ecology and evolution · 2021Article
- Mitochondrial Short-Term Plastic Responses and Long-Term Evolutionary Dynamics in Animal Species.Genome biology and evolution · 2021Review
- Sibling rivalry versus mother's curse: can kin competition facilitate a response to selection on male mitochondria?Proceedings. Biological sciences · 2020Article
- Mitonuclear conflict and cooperation govern the integration of genotypes, phenotypes and environments.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- Sperm competitive advantage of a rare mitochondrial haplogroup linked to differential expression of mitochondrial oxidative phosphorylation genes.Journal of evolutionary biology · 2019Article
- Temperature-Sensitive Reproduction and the Physiological and Evolutionary Potential for Mother's Curse.Integrative and comparative biology · 2019Article
- Sexual conflict through mother's curse and father's curse.Theoretical population biology · 2019Article
- Coadaptation of mitochondrial and nuclear genes, and the cost of mother's curse.Proceedings. Biological sciences · 2018Article
- Population genetics of sexual conflict in the genomic era.Nature reviews. Genetics · 2017Review
- Sexual conflict explains the extraordinary diversity of mechanisms regulating mitochondrial inheritance.BMC biology · 2017Article
- Sex-specific influences of mtDNA mitotype and diet on mitochondrial functions and physiological traits in Drosophila melanogaster.PloS one · 2017Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Many essential organelles and endosymbionts exhibit a strict matrilineal pattern of inheritance. The absence of paternal transmission of such extranuclear components is thought to preclude a response to selection on their effects on male viability and fertility. We overturn this dogma by showing that two mechanisms, inbreeding and kin selection, allow mitochondria to respond to selection on both male viability and fertility. Even modest levels of inbreeding allow such a response to selection when there are direct fitness effects of mitochondria on male fertility because inbreeding associates male fertility traits with mitochondrial matrilines. Male viability effects of mitochondria are also selectable whenever there are indirect fitness effects of males on the fitness of their sisters. When either of these effects is sufficiently strong, we show that there are conditions that allow the spread of mitochondria with direct effects that are harmful to females, contrary to standard expectation. We discuss the implications of our findings for the evolution of organelles and endosymbionts and genomic conflict.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.