ReviewMolecular neurobiology2009
Cellular and molecular neurobiology of brain preconditioning.
Review in Molecular neurobiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Nucleus accumbens CD81 regulates methamphetamine-induced locomotor activity, conditioned reward, and reinstatement in male and female rats.Psychopharmacology · 2026Article
- Optogenetic mitochondrial preconditioning enhances cardiomyocyte survival under stress.Journal of molecular and cellular cardiology · 2025Article
- The E3-ligase Siah2 activates mitochondrial quality control in neurons to maintain energy metabolism during ischemic brain tolerance.Cell death & disease · 2025Article
- Tissue-type plasminogen activator induces TNF-α-mediated preconditioning of the blood-brain barrier.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Footshock-Induced Abstinence from Compulsive Methamphetamine Self-administration in Rat Model Is Accompanied by Increased Hippocampal Expression of Cannabinoid Receptors (CB1 and CB2).Molecular neurobiology · 2022Article
- Mitochondria as the memory of preconditioning.Conditioning medicine · 2021Article
- Sevoflurane postconditioning improves spatial learning and memory ability involving mitochondrial permeability transition pore in hemorrhagic shock and resuscitation rats.Brain and behavior · 2020Article
- Implications of alpha-synuclein nitration at tyrosine 39 in methamphetamine-induced neurotoxicityNeural regeneration research · 2019Article
- Cross tolerance: a tread to decipher the code of endogenous global cerebral resistance.Neural regeneration research · 2016Article
- Involvement of GluR2 up-regulation in neuroprotection by electroacupuncture pretreatment via cannabinoid CB1 receptor in mice.Scientific reports · 2015Article
- Genetic animal models of preconditioning.Translational stroke research · 2013Review
- Mitochondrial biogenesis contributes to ischemic neuroprotection afforded by LPS pre-conditioning.Journal of neurochemistry · 2012Article
- Trauma-induced alterations in cognition and Arc expression are reduced by previous exposure to 56Fe irradiation.Hippocampus · 2012Article
- From rapid to delayed and remote postconditioning: the evolving concept of ischemic postconditioning in brain ischemia.Current drug targets · 2012Review
- Endothelial cells and astrocytes: a concerto en duo in ischemic pathophysiology.International journal of cell biology · 2012Article
- NAD+ depletion or PAR polymer formation: which plays the role of executioner in ischaemic cell death?Acta physiologica (Oxford, England) · 2011Review
- Chronic methamphetamine administration causes differential regulation of transcription factors in the rat midbrain.PloS one · 2011Article
- Long-term protective effects of methamphetamine preconditioning against single-day methamphetamine toxic challenges.Current neuropharmacology · 2011Article
- Methamphetamine preconditioning causes differential changes in striatal transcriptional responses to large doses of the drug.Dose-response : a publication of International Hormesis Society · 2011Article
- Mitochondria: the missing link between preconditioning and neuroprotection.Journal of Alzheimer's disease : JAD · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The tolerant brain which is a consequence of adaptation to repeated nonlethal insults is accompanied by the upregulation of protective mechanisms and the downregulation of prodegenerative pathways. During the past 20 years, evidence has accumulated to suggest that protective mechanisms include increased production of chaperones, trophic factors, and other antiapoptotic proteins. In contrast, preconditioning can cause substantial dampening of the organism's metabolic state and decreased expression of proapoptotic proteins. Recent microarray analyses have also helped to document a role of several molecular pathways in the induction of the brain refractory state. The present review highlights some of these findings and suggests that a better understanding of these mechanisms will inform treatment of a number of neuropsychiatric disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.