ReviewNature clinical practice. Gastroenterology & hepatology2009
How to critically appraise an article.
Review in Nature clinical practice. Gastroenterology & hepatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 12 syntheses or guidelines pooled it.
- Interpretability of Clinical Decision Support Systems Based on Artificial Intelligence from Technological and Medical Perspective: A Systematic Review.Journal of healthcare engineering · 2023Pooled it
- Autopsy findings of COVID-19 in children: a systematic review and meta-analysis.Forensic science, medicine, and pathology · 2022Pooled it
- Pitfalls in complement analysis: A systematic literature review of assessing complement activation.Frontiers in immunology · 2022Pooled it
- Strength-based interventions for HIV prevention and sexual risk reduction among girls and young women: A resilience-focused systematic review.Global public health · 2019Pooled it
- Updated evidence of the association between toxocariasis and epilepsy: Systematic review and meta-analysis.PLoS neglected tropical diseases · 2018Pooled it
- Radiological and clinical outcomes of novel Ti/PEEK combined spinal fusion cages: a systematic review and preclinical evaluation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017Pooled it
- Internet Health Information Seeking and the Patient-Physician Relationship: A Systematic Review.Journal of medical Internet research · 2017Pooled it
- Avian influenza in Latin America: A systematic review of serological and molecular studies from 2000-2015.PloS one · 2017Pooled it
- Diversity of susceptible hosts in canine distemper virus infection: a systematic review and data synthesis.BMC veterinary research · 2016Pooled it
- What do people really think of generic medicines? A systematic review and critical appraisal of literature on stakeholder perceptions of generic drugs.BMC medicine · 2015Pooled it
- A systematic review of the literature on 'medication wastage': an exploration of causative factors and effect of interventions.International journal of clinical pharmacy · 2014Pooled it
- Opportunities for engaging low-income, vulnerable populations in health care: a systematic review of homeless persons' access to and use of information technologies.American journal of public health · 2013Pooled it
- Reporting and critical appraisal of evidence-based research: Making the journal club most effective.Indian journal of pharmacology · 2026Review
- Deep Brain Stimulation in Treatment-Resistant Psychiatric Disorders: Efficacy, Safety, and Future Directions.Brain sciences · 2025Review
- Role for neurological and immunological resilience in the pathway of the aging muscle powerpenia: InCHIANTI study longitudinal results.GeroScience · 2025Article
- Exploring the Potential of Microservices in Internet of Things: A Systematic Review of Security and Prospects.Sensors (Basel, Switzerland) · 2024Review
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- An integrative review on individual determinants of enrolment in National Health Insurance Scheme among older adults in Ghana.BMC primary care · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Critical appraisal is a systematic process used to identify the strengths and weaknesses of a research article in order to assess the usefulness and validity of research findings. The most important components of a critical appraisal are an evaluation of the appropriateness of the study design for the research question and a careful assessment of the key methodological features of this design. Other factors that also should be considered include the suitability of the statistical methods used and their subsequent interpretation, potential conflicts of interest and the relevance of the research to one's own practice. This Review presents a 10-step guide to critical appraisal that aims to assist clinicians to identify the most relevant high-quality studies available to guide their clinical practice.
Indexed as
Identifiers
19153565What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.