ReviewThe Journal of antimicrobial chemotherapy2009
The impact of mental health and traumatic life experiences on antiretroviral treatment outcomes for people living with HIV/AIDS.
Review in The Journal of antimicrobial chemotherapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 4 syntheses or guidelines pooled it, 158 citations in OpenAlex.
- The Prevalence of Post-Traumatic Stress Disorder among People Living with HIV/AIDS: a Systematic Review and Meta-Analysis.The Psychiatric quarterly · 2020Pooled it
- Magnitude and predictors of common mental disorder among people with HIV/AIDS in Ethiopia: a systematic review and meta-analysis.BMC public health · 2020Pooled it
- Pooled it
- Mental health outcomes in HIV and childhood maltreatment: a systematic review.Systematic reviews · 2012Pooled it
- Rumination influences the relationship between trauma and depression over time among youth living with HIV.Journal of affective disorders · 2023Trial
- The impact of substance use, sexual trauma, and intimate partner violence on sexual risk intervention outcomes in couples: a randomized trial.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2013Trial
- A randomized controlled trial of an HIV/AIDS Symptom Management Manual for depressive symptoms.AIDS care · 2013Trial
- Examining Mental Health, Social Support and Resilience Among Immigrant Women Living with HIV in the British Columbia CARMA-CHIWOS Collaboration (BCC3) Study.AIDS and behavior · 2026Article
- Article
- The effects of psychological functioning on substance use and treatment outcomes among people with HIV.Scientific reports · 2025Article
- High Prevalence of Posttraumatic Stress Disorder Symptoms Found in Well-Treated People with HIV after the Introduction of Patient-Reported Outcome Measures.AIDS and behavior · 2025Article
- Facilitators and Barriers to adherence to antiretroviral therapy among incarcerated people living with HIV in Iran: insights from a qualitative study.Harm reduction journal · 2025Article
- A global scoping review of task shifting and sharing interventions to improve the mental health of people living with HIV/AIDS.Global mental health (Cambridge, England) · 2025Review
- Mental health challenges among adolescents and young adults with perinatally acquired HIV: Key findings from the I'mPossible program in India.PLOS mental health · 2025Article
- Burnout Among Service Providers for People Living with HIV: Factors Related to Coping and Resilience.Journal of racial and ethnic health disparities · 2024Article
- Associations between adverse childhood experiences, viral suppression, and quality of life among persons living with HIV in Washington state.AIDS care · 2024Article
- Underestimation of potentially traumatic events resulting from underreporting of physical and sexual violence among people entering care for HIV in Cameroon.Psychological trauma : theory, research, practice and policy · 2024Article
- Article
- Influence of childhood trauma, HIV infection, alcohol use disorder, and resilience on health-related quality of life in adulthood.Journal of psychiatric research · 2023Article
- Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Potent antiretroviral therapy (ART) has transformed HIV from a death sentence to a chronic illness. Accordingly, the goal of HIV care has shifted from delaying death to achieving optimal health outcomes through ART treatment. ART treatment success hinges on medication adherence. Extensive research has demonstrated that the primary barriers to ART adherence include mental illness, especially depression and substance abuse, as well as histories of traumatic experiences such as childhood sexual and physical abuse. These psychosocial factors are highly prevalent in people living with HIV/AIDS (PLWHA) and predict poor ART adherence, increased sexual risk behaviours, ART treatment failure, HIV disease progression and higher mortality rates. The efficacy of standard mental health interventions, such as antidepressant treatment and psychotherapy, has been well-defined, and a small but growing body of research demonstrates the potential for such interventions to improve ART adherence and reduce sexual risk behaviours. Despite this evidence, mental disorders in PLWHA frequently go undiagnosed and untreated. Challenges to the provision of mental healthcare for PLWHA in HIV clinical settings include time and resource constraints, lack of expertise in psychiatric diagnosis and treatment, and lack of available mental health referral services. Future research should prioritize the evaluation of mental health interventions that are cost-effective and feasible for widespread integration into HIV clinical care; the impact of such interventions on ART adherence and clinical outcomes; and interventions to identify individuals with histories of traumatic experiences and to elucidate the mechanisms through which such histories pose barriers to effective HIV treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.