ArticleSocial science & medicine (1982)2009
Early origins of health disparities: burden of infection, health, and socioeconomic status in U.S. children.
Article in Social science & medicine (1982), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06002685 (Effects of Attachment-Based Intervention on Low-Income Latino Children's Emerging Health Outcomes), which is not on this map. Cited by 82 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Attachment-Based Intervention on Low-Income Latino Children's Emerging Health Outcomes
Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it, 174 citations in OpenAlex.
- Seroprevalence of hepatitis E virus infection in the Americas: Estimates from a systematic review and meta-analysis.PloS one · 2022Pooled it
- A natural product telomerase activator as part of a health maintenance program.Rejuvenation research · 2011Trial
- A Pathogen Penalty? Associations Between Persistent Infections and Biological Aging in the US.The Journal of infectious diseases · 2026Article
- Life course socioeconomic disadvantage and persistent infection burden: Links to cellular immunosenescence in U.S. young adults.Social science & medicine (1982) · 2025Article
- Early-life infectious disease exposure, the "hygiene hypothesis," and lifespan: Evidence from hookworm disease.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Health impact of a hypothetical intervention on immune burden of cytomegalovirus (CMV) among older adults in the US: a prospective analysis of the Health and Retirement Study Cohort.Lancet regional health. Americas · 2025Article
- Evaluating the relationship between familial poverty,Frontiers in public health · 2025Article
- The association between inflammatory cytokines and sarcopenia-related traits: a bi-directional Mendelian randomization study.European journal of clinical nutrition · 2024Article
- The embodiment of the neighborhood socioeconomic environment in the architecture of the immune system.PNAS nexus · 2024Article
- Intersectional inequalities in paediatric infectious diseases: a national cohort study in Sweden.Journal of epidemiology and community health · 2024Article
- Parental income gradients in child and adolescent mortality: Norwegian trends over half a century.Scandinavian journal of public health · 2024Article
- Article
- The association between socioeconomic status and C-reactive protein in Bayesian perspective.SSM - population health · 2023Article
- The Long Arm of childhood hypothesis and systematic low-grade inflammation: Evidence from parental education of older European adults.SSM - population health · 2023Article
- Review
- First-generation College Students Have Greater Systemic Inflammation than Continuing-Generation College Students Following the Initial College Transition: A Brief Report.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Article
- Socioeconomic and race/ethnic differences in immunosenescence: Evidence from the Health and Retirement Study.Brain, behavior, and immunity · 2023Article
- Article
- Parental education and hospitalisations among Pacific children: A cross-sectional study using linked administrative data in New Zealand's Integrated Data Infrastructure.Journal of the Royal Society of New Zealand · 2023Article
- Blood DNA methylation signatures are associated with social determinants of health among survivors of childhood cancer.Epigenetics · 2022Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Recent work in biodemography has suggested that lifetime exposure to infection and inflammation may be an important determinant of later-life morbidity and mortality. Early exposure to infections during critical periods can predispose individuals to chronic disease, in part through the reallocation of energy away from development needed for immune and inflammatory responses. Furthermore, markers of inflammation are known to vary by socioeconomic status in adults and may contribute to overall socioeconomic health inequalities, but little is known about how the sources of this inflammation differ over the life course. This paper uses novel biomarker data from the Third National Health and Nutrition Examination Survey (NHANES III) to test the association of the burden of common chronic infections (Helicobacter pylori (H. pylori), cytomegalovirus (CMV), herpes simplex virus-1 (HSV-1), hepatitis A and hepatitis B) with height-for-age and asthma/chronic respiratory conditions in U.S. children ages 6 and older, and the association of these chronic infections to children's socioeconomic status. A higher burden of infection is found to be associated with lower height-for-age as well as an increased likelihood of asthma net of race/ethnicity, family income, and parental education. Children with lower family income, lower parental education, and non-white race/ethnicity have a higher likelihood of infection with several individual pathogens as well as the overall burden of infection. Differential exposure and/or susceptibility to infections may be one mechanism through which early social factors get embodied and shape later-life health outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.