ArticleThe EMBO journal1991
Transfer of rpl22 to the nucleus greatly preceded its loss from the chloroplast and involved the gain of an intron.
Article in The EMBO journal, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers.
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Who cites it
131 citing papers in PubMed.
- Article
- Comparative chloroplast genome analysis of fourFrontiers in plant science · 2026Article
- A Comprehensive Comparative Analysis and Phylogenetic Investigation of the Chloroplast Genome Sequences in FourCurrent issues in molecular biology · 2025Article
- Phylogenomic Analyses and DNA Barcoding Development Within Moraceae: Insights Into Genomic Features, Mutational Hotspots, and Adaptive Evolution.Ecology and evolution · 2025Article
- Reverse genetics in the Arabidopsis chloroplast genome identifies rps16 as a transcribed pseudogene.The Plant journal : for cell and molecular biology · 2025Article
- Complete Chloroplast Genome Analysis ofPlants (Basel, Switzerland) · 2025Article
- Comparative analysis of chloroplast genomes in three Araceae species: genomic difference, genetic distance and species morphology association.Frontiers in genetics · 2025Article
- Article
- Complete Chloroplast Genome ofGenes · 2024Article
- Chloroplast genomes of Caragana tibetica and Caragana turkestanica: structures and comparative analysis.BMC plant biology · 2024Article
- Chloroplast genome analyses of Caragana arborescens and Caragana opulens.BMC genomic data · 2024Article
- Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting.Frontiers in plant science · 2024Article
- A Comprehensive Analysis of Chloroplast Genome Provides New Insights into the Evolution of the GenusInternational journal of molecular sciences · 2023Article
- Comparative Analysis of Chloroplast Genome ofInternational journal of molecular sciences · 2023Article
- Chloroplast genome assembly ofFrontiers in plant science · 2023Article
- Article
- Gene loss, genome rearrangement, and accelerated substitution rates in plastid genome of Hypericum ascyron (Hypericaceae).BMC plant biology · 2022Article
- Article
- Genome-Wide Insights Into the Organelle Translocation of Photosynthetic NDH-1 Genes During Evolution.Frontiers in microbiology · 2022Article
- Phylogenetic relationships in the Sorghum genus based on sequencing of the chloroplast and nuclear genes.The plant genome · 2021Article
71 more citing papers are in PubMed but not listed here.
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5 authors.
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Abstract
Most chloroplast and mitochondrial proteins are encoded by nuclear genes that once resided in the organellar genomes. Transfer of most of these genes appears to have occurred soon after the endosymbiotic origin of organelles, and so little is known about the process. Our efforts to understand how chloroplast genes are functionally transferred to the nuclear genome have led us to discover the most recent evolutionary gene transfer yet described. The gene rpl22, encoding chloroplast ribosomal protein CL22, is present in the chloroplast genome of all plants examined except legumes, while a functional copy of rpl22 is located in the nucleus of the legume pea. The nuclear rpl22 gene has acquired two additional domains relative to its chloroplast ancestor: an exon encoding a putative N-terminal transit peptide, followed by an intron which separates this first exon from the evolutionarily conserved, chloroplast-derived portion of the gene. This gene structure suggests that the transferred region may have acquired its transit peptide by a form of exon shuffling. Surprisingly, phylogenetic analysis shows that rpl22 was transferred to the nucleus in a common ancestor of all flowering plants, at least 100 million years preceding its loss from the legume chloroplast lineage.
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