ReviewWorld journal of gastroenterology2009
Mycobacterium avium subspecies paratuberculosis and its relationship with Crohn's disease.
Review in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed.
- Article
- TLR Signaling Beyond Immunity: Emerging Roles in Cell Migration, Metabolism, Development, and Host-Microbiome Crosstalk.Biology · 2026Review
- Article
- Physiological, genetical and morphological alterations in Mycobacterium avium subsp. paratuberculosis mutants generated with the CRISPRi system.BMC microbiology · 2026Article
- A comprehensive review of paratuberculosis in animals and its implications for public health.Open veterinary journal · 2024Review
- Genetic Involvement ofInternational journal of molecular sciences · 2021Review
- Application of Volatilome Analysis to the Diagnosis of Mycobacteria Infection in Livestock.Frontiers in veterinary science · 2021Review
- Detection of Wood Mice (Microorganisms · 2020Article
- Mycobacterium avium paratuberculosis and Mycobacterium avium complex and related subspecies as causative agents of zoonotic and occupational diseases.Journal of cellular physiology · 2019Review
- Article
- First molecular epidemiological study of Mycobacterium avium subsp. paratuberculosis in cattle and buffalo from different regions of Brazil.Tropical animal health and production · 2018Article
- Immunopathogenesis of granulomas in chronic autoinflammatory diseases.Clinical & translational immunology · 2016Review
- Persistence of bacterial indicators and zoonotic pathogens in contaminated cattle wastes.BMC microbiology · 2016Article
- Isolation and identification of nontuberculous mycobacteria from hospitalized patients and drinking water samples--examination of their correlation by chemometrics.Environmental monitoring and assessment · 2016Article
- Avian Mycobacteriosis: Still Existing Threat to Humans.BioMed research international · 2016Review
- Article
- Resolution of Crohn's disease and complex regional pain syndrome following treatment of paratuberculosis.World journal of gastroenterology · 2015Article
- Species-specific engagement of human nucleotide oligomerization domain 2 (NOD)2 and Toll-like receptor (TLR) signalling upon intracellular bacterial infection: role of Crohn's associated NOD2 gene variants.Clinical and experimental immunology · 2015Article
- Pathogenesis of Crohn's disease: Bug or no bug.World journal of gastrointestinal pathophysiology · 2015Review
- In Vivo Volatile Organic Compound Signatures of Mycobacterium avium subsp. paratuberculosis.PloS one · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hypothesis postulating that Mycobacterium avium paratuberculosis (MAP) is the cause of Crohn's disease (CD) has been circulating for many years. Advances in molecular techniques, such as polymerase chain reaction and culture methods, have enabled researchers to demonstrate that there is an association between MAP and CD. Recently, genome-wide association studies have identified novel susceptibility genes for CD, which are critical for generation of an adaptive immune response that is protective against intracellular pathogens, including M. tuberculosis infection. However, the role of MAP as a cause of CD suffered a setback with the report that administration of antimycobacterial therapy failed to lead to a sustained response in CD patients. Accordingly, this review sought neither to confirm nor refute this, but instead to survey recent literature on the role of MAP in CD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.