ArticleAngewandte Chemie (International ed. in English)2009
Plug-based microfluidics with defined surface chemistry to miniaturize and control aggregation of amyloidogenic peptides.
Article in Angewandte Chemie (International ed. in English), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Microfluidics-Based Systems in Diagnosis of Alzheimer's Disease and Biomimetic Modeling.Micromachines · 2020Review
- Systematic Investigation of Insulin Fibrillation on a Chip.Molecules (Basel, Switzerland) · 2020Article
- Monitoring microbial metabolites using an inductively coupled resonance circuit.Scientific reports · 2015Article
- The amyloid state and its association with protein misfolding diseases.Nature reviews. Molecular cell biology · 2014Review
- Article
- Processing of nanolitre liquid plugs for microfluidic cell-based assays.Science and technology of advanced materials · 2012Article
- Observation of spatial propagation of amyloid assembly from single nuclei.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Nanoliter multiplex PCR arrays on a SlipChip.Analytical chemistry · 2010Article
- Evolution of catalysts directed by genetic algorithms in a plug-based microfluidic device tested with oxidation of methane by oxygen.Journal of the American Chemical Society · 2010Article
- SlipChip.Lab on a chip · 2009Article
- Laterally mobile, functionalized self-assembled monolayers at the fluorous-aqueous interface in a plug-based microfluidic system: characterization and testing with membrane protein crystallization.Journal of the American Chemical Society · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Small with control: For miniaturization of protein aggregation experiments the interfacial chemistry must be controlled to avoid protein aggregation caused by interfacial adsorption. Plug-based microfluidics with defined surface chemistry (see schematic picture) can then be used to perform hundreds of aggregation experiments with volume-limited samples, such as cerebrospinal fluid from mice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.