Evidence map›Paper›PMID 19152326›Full record

ArticleJournal of the American Chemical Society2009

Biomembrane sensitivity to structural changes in bound polymers.

Alexander A Yaroslavov, Tatiana A Sitnikova, Anna A Rakhnyanskaya, Ekaterina G Yaroslavova, Dmitry A Davydov, Tatiana V Burova, Valery Ya Grinberg, Lei Shi, Fredric M Menger

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander A YaroslavovDepartment of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, Moscow, RF.
Tatiana A Sitnikova
Anna A Rakhnyanskaya
Ekaterina G Yaroslavova
Dmitry A Davydov
Tatiana V Burova
Valery Ya Grinberg
Lei Shi
Fredric M Menger

Funding

CYTOMIMETIC ORGANIC CHEMISTRYR37GM021457 · NIGMS · EMORY UNIVERSITY · PI MENGER, FREDRIC M · 1998 to 2007
$2.2M
Polyamphiphile-Mediated Effects in Lipid VesiclesR03TW005555 · FIC · EMORY UNIVERSITY · PI MENGER, FREDRIC M · 2001 to 2007
$224k
FIC NIH HHS R03 TW005555FIC NIH HHS TW05555NIGMS NIH HHS R37 GM021457
6 · The paper itself

Abstract

Anionic liposomes containing a 4:1 molar ratio of neutral to anionic phospholipids were treated with an excess of five zwitterionic polymers differing only in the spacer length separating their cationic and anionic moieties. Although the polymers do not disrupt the structural integrity of the liposomes, they can induce spacer-dependent molecular rearrangements within the liposomes. Thus, the following were observed: spacer length = 1, no binding to the liposomes; spacer length = 2, adsorption to the liposomes, but no molecular rearrangement; spacer length = 3, lateral lipid segregation but little or no flip-flop; spacer length = 4 or 5, lateral lipid segregation and flip-flop. These diverse behaviors are relevant to the use of biomedical formulations where polyelectrolytes play a role.

Indexed as

1,2-DipalmitoylphosphatidylcholineCalorimetry, Differential ScanningLipid BilayersLiposomesModels, MolecularPhosphatidylcholinesPhospholipidsPolyvinylsSpectrometry, Fluorescence1,2-Dipalmitoylphosphatidylcholine1,2-oleoylphosphatidylcholineLipid BilayersLiposomesPhosphatidylcholinesPhospholipidspoly(4-vinylpyridine)Polyvinyls

Identifiers

PMID19152326
PMCPMC2645027

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.