SynthesisJournal of substance abuse treatment2009
Meta-analysis of depression and substance use among individuals with alcohol use disorders.
Synthesis in Journal of substance abuse treatment, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
130 citing papers in PubMed, 2 syntheses or guidelines pooled it, 330 citations in OpenAlex.
- Characteristics of non-fatal self-poisoning in Sri Lanka: a systematic review.BMC public health · 2013Pooled it
- Disability associated with alcohol abuse and dependence.Alcoholism, clinical and experimental research · 2010Pooled it
- Gender and addiction and other mental disorders comorbidity: sociodemographic, clinical, and treatment differences.Archives of women's mental health · 2023Trial
- Mediation pathways for reduced substance use among parents in South Africa: a randomized controlled trial.BMC public health · 2021Trial
- A randomized controlled trial of an Internet delivered dialectical behavior therapy skills training for suicidal and heavy episodic drinkers.Journal of affective disorders · 2018Trial
- Adverse impact of marijuana use on clinical outcomes among psychiatry patients with depression and alcohol use disorder.Psychiatry research · 2018Trial
- The role of hazardous drinking reductions in predicting depression and anxiety symptom improvement among psychiatry patients: A longitudinal study.Journal of affective disorders · 2016Trial
- Epidemiology of pain among outpatients in methadone maintenance treatment programs.Drug and alcohol dependence · 2013Trial
- A pilot study of interpersonal psychotherapy for alcohol-dependent women with co-occurring major depression.Substance abuse · 2013Trial
- The moderating effects of group cognitive-behavioral therapy for depression among substance users.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2012Trial
- Effects of pretreatment and posttreatment depressive symptoms on alcohol consumption following treatment in Project MATCH.Journal of studies on alcohol and drugs · 2010Trial
- Impact of Depressive Symptom Severity on Buprenorphine/Naloxone and Methadone Outcomes in People With Prescription-Type Opioid Use Disorder: Results From a Pragmatic Randomized Controlled Trial.Journal of dual diagnosisTrial
- Exposure to disaster information on social media, depressive symptoms, and alcohol and cannabis use in the aftermath of two natural disasters.Addictive behaviors reports · 2026Article
- Risk factors for alcohol-related injury experienced within a year: results of a nationwide large-scale internet survey.Addictive behaviors reports · 2026Article
- Co-occurrence of alcohol use disorder and mood disorders in the adult population in Poland: results from the EZOP II study.Postepy psychiatrii neurologii · 2026Article
- Reciprocal longitudinal relationship between depressive symptoms and problematic alcohol use: a random intercept cross-lagged panel model including a nationwide sample of Korean adults.European archives of psychiatry and clinical neuroscience · 2026Article
- Alcohol and Substance Use After Bariatric Surgery: Nutritional Risks and Clinical Implications in Long-Term Postoperative Care.Nutrients · 2026Review
- Health's influence on alcohol use-a longitudinal study of working adults in Sweden.European journal of public health · 2026Article
- Examination of the moderating role of internalizing symptoms in the direct and indirect relationships between alcohol use severity, rumination, and suicidal ideation.Journal of affective disorders · 2026Article
- Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth.Molecular psychiatry · 2026Article
70 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
The relationships of depression with alcohol and drug use and impairment were examined. Additional analyses were conducted to examine moderators of these associations. Empirical reports on adults with alcohol abuse or dependence published in English in peer-reviewed journals since 1986 that contained data on depression and substance use variable(s) were obtained using a systematic search. The search yielded 74 studies including 58 reports from clinical venues, 10 that were community based, and 6 with subjects from both settings. As hypothesized, the analyses showed that depression is associated with concurrent alcohol use and impairment and drug use and impairment. Effect sizes were small. Depression was also related to future alcohol use and impairment, an earlier age of onset of an alcohol use disorder, and higher treatment participation. Age moderated the association between depression and alcohol use and impairment such that the association was stronger in older samples.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.