ArticlePlant cell reports2009
Pb/Cu effects on the organization of microtubule cytoskeleton in interphase and mitotic cells of Allium sativum L.
Article in Plant cell reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 57 citations in OpenAlex.
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- Investigation of multidirectional toxicity induced by high-dose molybdenum exposure with Allium test.Scientific reports · 2024Article
- Effects of Heavy Metals on Stomata in Plants: A Review.International journal of molecular sciences · 2023Review
- Recent advances in physiological and molecular mechanisms of heavy metal accumulation in plants.Environmental science and pollution research international · 2021Review
- Plant Recovery after Metal Stress-A Review.Plants (Basel, Switzerland) · 2021Review
- Main Molecular Pathways Associated with Copper Tolerance Response inPlants (Basel, Switzerland) · 2021Article
- Cadmium toxicity and its relationship with disturbances in the cytoskeleton, cell cycle and chromosome stability.Ecotoxicology (London, England) · 2019Article
- Article
- Differential expression of poplar sucrose nonfermenting1-related protein kinase 2 genes in response to abiotic stress and abscisic acid.Journal of plant research · 2017Article
- Hexavalent chromium-induced differential disruption of cortical microtubules in some Fabaceae species is correlated with acetylation of α-tubulin.Protoplasma · 2016Article
- Aberration of mitosis by hexavalent chromium in some Fabaceae members is mediated by species-specific microtubule disruption.Environmental science and pollution research international · 2015Article
- Cadmium affects microtubule organization and post-translational modifications of tubulin in seedlings of soybean (Glycine max L.).Frontiers in plant science · 2015Article
- The nitrate reductase inhibitor, tungsten, disrupts actin microfilaments in Zea mays L.Protoplasma · 2014Article
- Effect of lead on root growth.Frontiers in plant science · 2013Article
- Effects of hexavalent chromium on microtubule organization, ER distribution and callose deposition in root tip cells of Allium cepa L.Protoplasma · 2012Article
- Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation.Disease models & mechanismsArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effects of lead and copper on the arrangement of microtubule (MT) cytoskeleton in root tip cells of Allium sativum L. were investigated. Batch cultures of garlic were carried out under defined conditions in the presence 10(-4) M Pb/Cu of various duration treatments. With tubulin immunolabelling and transmission electron microscopy (TEM), we found four different types of MT structures depending on the cell cycle stage: the interphase array, preprophase band, mitotic spindle and phragmoplast were typical for the control cells. Pb/Cu affected the mechanisms controlling the organization of MT cytoskeleton, and induces the following aberrations in interphase and mitotic cells. (1) Pb/Cu induced the formation of atypical MT arrays in the cortical cytoplasm of the interphase cells, consisting of skewed, wavy MT bundles, MT fragments and ring-like tubulin aggregations. (2) Pb/Cu disordered the chromosome movements carried out by the mitotic spindle. The outcome was chromosome aberrations, for example, chromosome bridges and chromosome stickiness, as well as inhibition of cells from entering mitosis. (3) Depending on the time of exposure, MTs disintegrated into shorter fragments or they completely disappeared, indicating MT depolymerization. (4) Different metals had different effects on MT organization. MTs were more sensitive to the pressure of Cu ions than Pb. Moreover, TEM observations showed that the MTs were relatively short and in some places wavy when exposed to 10(-4) M Pb/Cu solutions for 1-2 h. In many sections MTs were no longer visible with increasing duration of treatment (>4 h). Based on these results, we suggested that MT cytoskeleton is primarily responsible for Pb/Cu-associated toxicity and tolerance in plants.
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