Evidence map›Paper›PMID 19148215›Full record

ReviewThe Journal of investigative dermatology2009

The primary cilium: a small yet mighty organelle.

Mindy C DeRouen, Anthony E Oro

Open access · bronzeAbstract readCommentReview
In one paragraph

Review in The Journal of investigative dermatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. TGF-βJournal of molecular medicine (Berlin, Germany) · 2017
    Article
  4. Article
  5. Article
  6. Article
  7. Hedgehog signalling pathway: carcinogenesis and targeted therapy.Iranian journal of cancer prevention · 2013
    Review
  8. Wound healing - A literature review.Anais brasileiros de dermatologia
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mindy C DeRouenProgram in Epithelial Biology, Stanford University School of Medicine, Stanford, California 94305, USA.
Anthony E Oro
Stanford University · US

Funding

STROMAL REGULATION OF BASAL CELL CARCINOMA FORMATIONR01AR046786 · NIAMS · STANFORD UNIVERSITY · PI Anthony E Oro · 2001 to 2026
$9.5M
REGULATING GLI FUNCTION IN HAIR FOLLICLE PROGENITORSR01AR054780 · NIAMS · STANFORD UNIVERSITY · PI ORO, ANTHONY E · 2007 to 2017
$4.3M
BEG4/MIM FUNCTION IN EPITHELIAL NEOPLASIAR01AR052785 · NIAMS · STANFORD UNIVERSITY · PI ORO, ANTHONY E · 2007 to 2018
$4.0M
NIAMS NIH HHS R01 AR046786NIAMS NIH HHS R01 AR052785NIAMS NIH HHS R01 AR054780
6 · The paper itself

Abstract

Primary cilia are small, cylindrical membrane protrusions on most vertebrate cell types. Despite an unassuming appearance, this organelle has proven to be a veritable nexus of tightly regulated cell-signal reception between the epithelium and mesenchyme. In this issue, Lehman et al. describe the necessity of Ift88 and intraflagellar transport for signal reception of the sonic hedgehog pathway in the dermal papilla of developing hair follicles.

Indexed as

AnimalsCiliaEpithelial CellsHair FollicleHumans

Identifiers

PMID19148215
PMCPMC3777402
OpenAlexW1967140655

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.