ReviewCancer research2009
On the role of cell signaling models in cancer research.
Review in Cancer research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Establishment of a human 3D lung cancer model based on a biological tissue matrix combined with a Boolean in silico model.Molecular oncology · 2014Trial
- Mathematical models of intercellular signaling in breast cancer.Seminars in cancer biology · 2025Review
- Article
- Signaling cascades transmit information downstream and upstream but unlikely simultaneously.BMC systems biology · 2016Article
- MiR-204 inhibits human NSCLC metastasis through suppression of NUAK1.British journal of cancer · 2014Article
- Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo.Nature communications · 2013Article
- An integrated computational/experimental model of lymphoma growth.PLoS computational biology · 2013Article
- Dealing with diversity in computational cancer modeling.Cancer informatics · 2013Article
- Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics.Molecular bioSystems · 2012Article
- Integrated intravital microscopy and mathematical modeling to optimize nanotherapeutics delivery to tumors.AIP advances · 2012Article
- Kinase inhibitors can produce off-target effects and activate linked pathways by retroactivity.BMC systems biology · 2011Article
- Long signaling cascades tend to attenuate retroactivity.Biophysical journal · 2011Article
- Article
- Physical oncology: a bench-to-bedside quantitative and predictive approach.Cancer research · 2011Review
- Predictions of tumour morphological stability and evaluation against experimental observations.Journal of the Royal Society, Interface · 2011Article
- Nonlinear modelling of cancer: bridging the gap between cells and tumours.Nonlinearity · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The main objective of this review is to emphasize the role and importance of the careful mathematical/computational modeling of signaling networks for the understanding of aberrant signaling in cancer and for the development of targeted therapies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.