ReviewMolecules (Basel, Switzerland)2009
Vitamin B6: a long known compound of surprising complexity.
Review in Molecules (Basel, Switzerland), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
124 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pharmacological treatment strategies for antipsychotic-induced hyperprolactinemia: a systematic review and network meta-analysis.Translational psychiatry · 2022Pooled it
- Vitamin B6 in Elite Athletes: Potential Implications of High Intakes.Sports medicine (Auckland, N.Z.) · 2026Review
- Host-independent metagenomics reveal gut bacteria contribution to Delia antiqua growth by vitamin B6 provision.Insect molecular biology · 2026Article
- Metabolic Rewiring of the Shikimate Pathway Enables Rose-Scented Rice.Plant biotechnology journal · 2026Article
- Testing-Yield Mismatch in Inpatient Micronutrient Assessment in Inflammatory Bowel Disease: A Real-World Implementation-Gap Analysis.Nutrients · 2026Article
- Investigation of the effects of ampicillin and ceftazidime on Proteus mirabilis using metabolomic approaches and bioinformatics analyses.Folia microbiologica · 2026Article
- Quantitation of Vitamin B6 Vitamers and Glycosides in German Alcohol-Free and Full-Strength Beer by a Stable Isotope Dilution LC-MS/MS Method.Journal of agricultural and food chemistry · 2026Article
- Metabolic pathways linked to sarcopenia in the Bushehr Elderly Health Program: kynurenine, nicotinamide, B-vitamins, and sulfur amino acids.BMC geriatrics · 2026Article
- From Fly to Human: Translational Relevance ofInternational journal of molecular sciences · 2026Review
- Enhanced vitamin BSynthetic and systems biotechnology · 2026Article
- A Genome-Wide Mutant Screen Identifies XopN and XopX as Core Type III Effectors Required for Peach Infection byMicroorganisms · 2026Article
- The mitigation mechanism of exogenous pyridoxal-5-phosphate on Pb stress damage in Polygonatum Cyrtonema Hua by multi-omics combined analysis.BMC genomics · 2026Article
- Flavonoid-mediated bacterial spermidine biosynthesis enhances vitamin accumulation in tomato fruits.Nature communications · 2026Article
- Synergistic inhibition ofFrontiers in microbiology · 2026Article
- From Reshaped Metabolome to Repaired Skin: FermentedAntioxidants (Basel, Switzerland) · 2025Article
- Article
- Gut dysbiosis-induced vitamin B6 metabolic disorder contributes to chronic stress-related abnormal behaviors in a cortisol-independent manner.Gut microbes · 2025Article
- Metabolomic Profiling and Characterization of a Novel 3D Culture System for Studying Chondrocyte Mechanotransduction.Cellular and molecular bioengineering · 2025Article
- Article
- Nicotinamide and Pyridoxine in Muscle Aging: Nutritional Regulation of Redox, Inflammation, and Regeneration.Antioxidants (Basel, Switzerland) · 2025Review
64 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years vitamin B6 has become a focus of research describing the compound's critical function in cellular metabolism and stress response. For many years the sole function of vitamin B6 was considered to be that of an enzymatic cofactor. However, recently it became clear that it is also a potent antioxidant that effectively quenches reactive oxygen species and is thus of high importance for cellular well-being. In view of the recent findings, the current review takes a look back and summarizes the discovery of vitamin B6 and the elucidation of its structure and biosynthetic pathways. It provides a detailed overview on vitamin B6 both as a cofactor and a protective compound. Besides these general characteristics of the vitamin, the review also outlines the current literature on vitamin B6 derivatives and elaborates on recent findings that provide new insights into transport and catabolism of the compound and on its impact on human health.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.