Evidence map›Paper›PMID 19144726›Full record

ArticleThe American journal of clinical nutrition2009

Vegetable and fruit intakes and risk of Barrett's esophagus in men and women.

Olivia M Thompson, Shirley A A Beresford, Elizabeth A Kirk, Thomas L Vaughan

Open access · greenAbstract read
In one paragraph

Article in The American journal of clinical nutrition, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Global burden and epidemiology of Barrett oesophagus and oesophageal cancer.Nature reviews. Gastroenterology & hepatology · 2021
    Review
  5. Review
  6. Article
  7. Article
  8. Etiology and Prevention of Esophageal Cancer.Gastrointestinal tumors · 2016
    Review
  9. Article
  10. Review
  11. Screening for Barrett's esophagus and esophageal adenocarcinoma: rationale, recent progress, challenges, and future directions.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2015
    Review
  12. Article
  13. A clinical risk prediction model for Barrett esophagus.Cancer prevention research (Philadelphia, Pa.) · 2012
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Olivia M ThompsonNutritional Sciences Program, University of Washington, Seattle, WA, USA. thompsonom@mail.nih.gov
Shirley A A Beresford
Elizabeth A Kirk
Thomas L Vaughan
Fred Hutch Cancer Center · USUniversity of Washington · US

Funding

Biobehavioral Cancer Prevention and Control Training ProgramR25CA092408 · NCI · UNIVERSITY OF WASHINGTON · PI PATRICK, DONALD LEE · 2001 to 2015
$7.1M
ESTABLISHED INVESTIGATOR AWARD IN CANCER PREVENTION AND CONTROLK05CA124911 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI VAUGHAN, THOMAS L · 2007 to 2016
$1.6M
EPIDEMIOLOGY OF BARRETTS ESOPHAGUSR01CA072866 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI VAUGHAN, THOMAS L · 1997 to 2000
$543k
NCI NIH HHS 2R25 CA092408-06NCI NIH HHS K05 CA124911NCI NIH HHS R01 CA072866NCI NIH HHS R01 CA72866NCI NIH HHS R25 CA092408
6 · The paper itself

Abstract

backgroundBarrett's esophagus (BE) is a risk factor for esophageal adenocarcinoma. Modifiable risk factors for BE are largely unknown.

objectiveThe purpose of this study was to determine whether vegetable and fruit intakes are associated with BE risk.

designIn a case-control study based in western Washington State, we compared the vegetable and fruit intakes of 170 patients with newly diagnosed BE with those of 182 controls from the general population. Relations between vegetable and fruit intakes and BE were examined by using unconditional logistic regression to compute odds ratios (ORs) and corresponding 95% CIs.

resultsParticipants in the second (adjusted OR: 0.40; 95% CI: 0.23, 0.71) and third (adjusted OR: 0.33; 95% CI: 0.17, 0.63) tertiles of vegetable intake appeared to have a lower risk of BE (P for trend = 0.048) than did participants in the first tertile of vegetable intake. Similarly, participants in the second (adjusted OR: 0.49; 95% CI: 0.28, 0.86) and third (adjusted OR: 0.39; 95% CI: 0.21, 0.75) tertiles of combined vegetable and fruit intakes had a lower risk of BE (P for trend = 0.047) than did participants in the first tertile of vegetable and fruit intakes. Similar results were obtained in subanalyses limited to patients with visible and with long-segment BE.

conclusionsThe results support previous findings that increased intakes of vegetables and of vegetables and fruit are associated with a lower risk of BE in men and women. Prospective data that examine relations between diet and BE are needed.

Indexed as

FruitVegetablesAdultAgedAged, 80 and overBarrett EsophagusCase-Control StudiesEatingFemaleHumansLogistic ModelsMaleMiddle AgedSurveys and QuestionnairesYoung Adult

Identifiers

PMID19144726
PMCPMC2667660
OpenAlexW2168481577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.