ReviewGenome biology2008
Replication forks, chromatin loops and dormant replication origins.
Review in Genome biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Article
- Chromoanasynthesis.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Starting DNA Synthesis: Initiation Processes during the Replication of Chromosomal DNA in Humans.Genes · 2024Review
- The Protective Role of Dormant Origins in Response to Replicative Stress.International journal of molecular sciences · 2018Review
- Article
- The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability.Cell reports · 2016Article
- The cancer therapeutic potential of Chk1 inhibitors: how mechanistic studies impact on clinical trial design.British journal of clinical pharmacology · 2013Review
- Dormant origins, the licensing checkpoint, and the response to replicative stresses.Cold Spring Harbor perspectives in biology · 2012Review
- Replication origins run (ultra) deep.Nature structural & molecular biology · 2012Article
- Continued primer synthesis at stalled replication forks contributes to checkpoint activation.The Journal of cell biology · 2010Article
- Why are we where we are? Understanding replication origins and initiation sites in eukaryotes using ChIP-approaches.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2010Article
- Analysis of replication factories in human cells by super-resolution light microscopy.BMC cell biology · 2009Article
- Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion.The EMBO journal · 2009Article
- A model for DNA replication showing how dormant origins safeguard against replication fork failure.EMBO reports · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
When DNA replication is slowed down, normally dormant replication origins are activated. Recent work demonstrates that cells adapt by changing the organization of chromatin loops and maintaining the new pattern of origin use in subsequent cell cycles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.