Evidence map›Paper›PMID 19144121›Full record

ArticleDynamic medicine : DM2009

Acute exercise and oxidative stress: a 30 year history.

Kelsey Fisher-Wellman, Richard J Bloomer

3 registry-linked trialsAbstract read
In one paragraph

Article in Dynamic medicine : DM, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 238 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
238citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02837666 nacompletednot on this mapstarted 2017, after this paper: background citation

Independent and Synergistic Effect of Spirulina Maxima With Exercise on General Fitness, Lipid Profile and Antioxidant Capacity in Overweight and Obese Subjects

TypeinterventionalSponsorUniversidad Autonoma de Ciudad JuarezRan2017 to 2017Enrolled52ConditionsCardiovascular DiseasesArmsSupplementation with Spirulina maxima, Washout, Supplementation with placebo, Isoenergetic diet, Exercise program
NCT04366427 phase2completednot on this mapstarted 2020, after this paper: background citation

Effects of Enriched Oxygen Mixtures and Exercise on Oxidative Stress and Stem Cells Proliferation in Athletes.

TypeinterventionalSponsorUniversity of PadovaRan2020 to 2020Enrolled42ConditionsOxidative Stress, Stem Cell ResearchArmsL-HBO, HBO, 30% O2, 50% O2
NCT04959006 nacompletednot on this mapstarted 2021, after this paper: background citation

Investigating the Impact of a Natural Antioxidant Food Product on Exerciseinduced Oxidative Stress in Recreationally Active Participants

TypeinterventionalSponsorAnglia Ruskin UniversityRan2021 to 2021Enrolled30ConditionsOxidative Stress, Exercise RecoveryArmsAntioxidant supplement, Placebo
3 · Its place in the literature

Who cites it

238 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Neuroendocrinal and molecular basis of flight performance in locusts.Cellular and molecular life sciences : CMLS · 2022
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Synergistic Effects of High-Intensity Interval Training andInternational journal of molecular sciences · 2025
    Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Does Multi-Strain Probiotic Supplementation Impact the Effort Capacity of Competitive Road Cyclists?International journal of environmental research and public health · 2022
    Trial
  18. Trial
  19. Trial
  20. Trial

178 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kelsey Fisher-WellmanCardiorespiratory/Metabolic Laboratory, Department of Health and Sport Sciences, The University of Memphis, 161F Elma Neal Roane Fieldhouse, Memphis, TN 38152, USA.
Richard J Bloomer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The topic of exercise-induced oxidative stress has received considerable attention in recent years, with close to 300 original investigations published since the early work of Dillard and colleagues in 1978. Single bouts of aerobic and anaerobic exercise can induce an acute state of oxidative stress. This is indicated by an increased presence of oxidized molecules in a variety of tissues. Exercise mode, intensity, and duration, as well as the subject population tested, all can impact the extent of oxidation. Moreover, the use of antioxidant supplements can impact the findings. Although a single bout of exercise often leads to an acute oxidative stress, in accordance with the principle of hormesis, such an increase appears necessary to allow for an up-regulation in endogenous antioxidant defenses. This review presents a comprehensive summary of original investigations focused on exercise-induced oxidative stress. This should provide the reader with a well-documented account of the research done within this area of science over the past 30 years.

Identifiers

PMID19144121
PMCPMC2642810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.