ArticleRapid communications in mass spectrometry : RCM2009
Artifacts in Fourier transform mass spectrometry.
Article in Rapid communications in mass spectrometry : RCM, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Spectral averaging with outlier rejection algorithms to increase identifications in top-down proteomics.Proteomics · 2024Article
- SPIX: A new software package to reveal chemical reactions at trace amounts in very complex mixtures from high-resolution mass spectra dataset.Rapid communications in mass spectrometry : RCM · 2021Article
- Evaluation of Sibling and Twin Fragment Ions Improves the Structural Characterization of Proteins by Top-Down MALDI In-Source Decay Mass Spectrometry.Analytical chemistry · 2020Article
- A Miniaturized Fourier Transform Electrostatic Linear Ion Trap Mass Spectrometer: Mass Range and Resolution.Journal of the American Society for Mass Spectrometry · 2019Article
- New methods to identify high peak density artifacts in Fourier transform mass spectra and to mitigate their effects on high-throughput metabolomic data analysis.Metabolomics : Official journal of the Metabolomic Society · 2018Article
- A tutorial in small molecule identification via electrospray ionization-mass spectrometry: The practical art of structural elucidation.Mass spectrometry reviews · 2018Review
- Using fragmentation trees and mass spectral trees for identifying unknown compounds in metabolomics.Trends in analytical chemistry : TRAC · 2015Article
- Isobaric labeling-based relative quantification in shotgun proteomics.Journal of proteome research · 2014Review
- Mass spectral peak distortion due to Fourier transform signal processing.Journal of the American Society for Mass Spectrometry · 2014Article
- Fragmentation trees for the structural characterisation of metabolites.Rapid communications in mass spectrometry : RCM · 2012Article
- A gain and bandwidth enhanced transimpedance preamplifier for Fourier-transform ion cyclotron resonance mass spectrometry.The Review of scientific instruments · 2011Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Recent work on a new, higher sensitivity preamplifier design for Fourier transform ion cyclotron resonance mass spectrometry (FTICRMS) revealed a number of artifact peaks (spectral features) which do not contain useful chemical information. In order to determine the cause of these artifacts and eliminate them, these severely distorted spectra were compared with similarly distorted signal models. The source of several common signal processing artifacts was thereby determined and correlated to radio-frequency interference (RFI) noise and saturation of the amplifier and/or the digitizer. Under such conditions, the fast Fourier transform (FFT) generates spectral artifact peaks corresponding to harmonics and mixing frequencies of the real signal peaks and RFI frequencies. While this study was done using FTICRMS data, it is important to stress that these artifacts are inherent to the digitization and FFT process and thus are relevant to any FT-based MS instrument, including the orbitrap and FT ion trap.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.