Evidence map›Paper›PMID 19141366›Full record

ArticleEarly human development2009

Predictors of neurodevelopmental outcome for preterm infants with brain injury: MRI, medical and environmental factors.

Lina Kurdahi Badr, Susan Bookheimer, Isabell Purdy, Mary Deeb

Abstract readMulticenter Study
In one paragraph

Article in Early human development, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Regional brain volume reduction and cognitive outcomes in preterm children at low risk at 9 years of age.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017
    Article
  14. Comparison of preterm and term equivalent age MRI for the evaluation of preterm brain injury.Journal of perinatology : official journal of the California Perinatal Association · 2017
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lina Kurdahi BadrSchool of Nursing, Azusa Pacific University, Azusa, California 91702, USA. linakbadr@hotmail.com
Susan Bookheimer
Isabell Purdy
Mary Deeb

Funding

ZONA-FREE HAMSTER OVA ASSAY AS AN INDICATOR OF MALE FERTILITYM01RR000425 · NCRR · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI ANDERSON, GAIL V · 1985 to 2011
$74.2M
NEUROPLASTICITY OF BRAIN ASPHYXIATED INFANTSR01HD038600 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GARG, MEENA · 1999 to 2003
$911k
NCRR NIH HHS M01 RR000425NCRR NIH HHS M01RR00425NICHD NIH HHS R01 HD038600PHS HHS R01NCT00006516
6 · The paper itself

Abstract

This multi-center correlational prospective study examined early neonatal predictors of neurodevelopment in 59 premature infants (mean birth weight=1713.8+/-1242.5 g; mean gestational age=31.2+/-3.6 weeks) suspected to have sustained brain injury at birth. The mental and motor development of the infants selected from five university-affiliated hospitals was assessed at baseline (59 infants), 12 (55 infants), and 18 months (46 infants) using Bayley II scales. Factors correlating with Bayley II scores at 12 and 18 months included head circumference, results of neurological and magnetic resonance imaging (MRI) examination at baseline, environmental factors such as mother-infant interactions and levels of parental stress, and infant medical factors such as Apgar scores at 5 min and length of hospital stay. Multiple regression analyses distinguished the most significant predictors of mental and motor development. The best predictors of mental and motor development at 18 months were head circumference, neurological examinations, and MRI results. These findings suggest that in infants suspected of brain injury at birth, neurological assessments and head circumference measurements are just as predictive of developmental outcome at 18 months as MRI, and this is especially relevant in developing countries or other locations where MRI is not possible. The presence of this information may offer the potential of early tailored interventions to improve the mental and motor development of children in developing countries or other facilities where MRI is unavailable.

Indexed as

Child DevelopmentAdultBrain InjuriesCephalometryDiagnostic Techniques, NeurologicalFemaleHeadHumansInfant, NewbornInfant, PrematureMagnetic Resonance ImagingNervous SystemPregnancyProspective StudiesRisk Assessment

Identifiers

PMID19141366
PMCPMC2700235

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.