ArticleGynecologic oncology2009
A prospective study of quality of life among women undergoing risk-reducing salpingo-oophorectomy versus gynecologic screening for ovarian cancer.
Article in Gynecologic oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 86 citations in OpenAlex.
- Article
- Sexual function following risk-reducing salpingo-oophorectomy: a prospective cohort study.Sexual medicine · 2024Article
- Utility Scores for Risk-Reducing Mastectomy and Risk-Reducing Salpingo-Oophorectomy: Mapping to EQ-5D.Cancers · 2024Article
- Cancer Anxiety Mediates the Association Between Satisfaction With Medical Communication and Psychological Quality of Life After Prophylactic Bilateral Salpingo-Oophorectomy.Frontiers in psychology · 2022Article
- Patient reported experiences following laparoscopic prophylactic bilateral salpingo-oophorectomy or salpingectomy in an ambulatory care hospital.Familial cancer · 2021Article
- Prospective follow-up of quality of life for participants undergoing risk-reducing salpingo-oophorectomy or ovarian cancer screening in GOG-0199: An NRG Oncology/GOG study.Gynecologic oncology · 2020Article
- The Effect of Prophylactic Adnexectomy on the Quality of Life and Psychosocial Functioning of Women with theInternational journal of environmental research and public health · 2019Article
- Interventions to improve psychosocial well-being in female BRCA-mutation carriers following risk-reducing surgery.The Cochrane database of systematic reviews · 2019Review
- Ovarian cancer: Pathogenesis and current recommendations for prophylactic surgeryJournal of the Turkish German Gynecological Association · 2019Article
- Risk factors for sexual dysfunction in BRCA mutation carriers after risk-reducing salpingo-oophorectomy.Menopause (New York, N.Y.) · 2019Article
- Predictors of hysterectomy among married women 15-49 years in India.Reproductive health · 2018Article
- Quality of life following prophylactic gynecological surgery: experiences of female Lynch mutation carriers.Familial cancer · 2018Article
- Sexual health needs and educational intervention preferences for women with cancer.Breast cancer research and treatment · 2017Article
- Factors associated with deciding between risk-reducing salpingo-oophorectomy and ovarian cancer screening among high-risk women enrolled in GOG-0199: An NRG Oncology/Gynecologic Oncology Group study.Gynecologic oncology · 2017Article
- Premature ovarian insufficiency: the context of long-term effects.Journal of endocrinological investigation · 2016Review
- Genetic testing for hereditary cancer predisposition: BRCA1/2, Lynch syndrome, and beyond.Gynecologic oncology · 2016Review
- Uptake of risk-reducing salpingo-oophorectomy among female BRCA mutation carriers: experience at the National Cancer Center of Korea.Journal of cancer research and clinical oncology · 2016Article
- Long-term outcomes of risk-reducing surgery in unaffected women at increased familial risk of breast and/or ovarian cancer.Familial cancer · 2015Article
- Addressing sexual dysfunction after risk-reducing salpingo-oophorectomy: effects of a brief, psychosexual intervention.The journal of sexual medicine · 2015Article
- Relationship satisfaction predicts sexual activity following risk-reducing salpingo-oophorectomy.Journal of psychosomatic obstetrics and gynaecology · 2014Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThe primary objective of the study was to prospectively assess quality of life (QOL) among women at increased risk of ovarian cancer who are undergoing risk-reducing salpingo-oophorectomy (RRSO) or serial screening.
methodsWomen at increased risk of ovarian cancer who were undergoing RRSO were recruited into the study. At-risk women undergoing serial screening for early detection of ovarian cancer served as a comparison group. Participants completed measures of QOL, sexual functioning, body image, depressive symptoms, and a symptom checklist at baseline (prior to surgery for women obtaining RRSO), and then at 1-month, 6-months, and 12-months post baseline.
resultsWomen who underwent surgery reported poorer physical functioning, more physical role limitations, greater pain, less vitality, poorer social functioning, and greater discomfort and less satisfaction with sexual activities at 1-month assessment compared to baseline. In contrast, women undergoing screening experienced no significant decrements in QOL or sexual functioning at 1-month assessment. Most QOL deficits observed in the surgical group were no longer apparent by 6-month assessment. Women in the surgery group were more likely to report hot flashes and vaginal dryness, but over time, symptoms of vaginal discomfort decreased to a greater extent in women who had RRSO compared to women undergoing screening. No differences in body image or depressive symptoms were observed between the two groups at any time point.
conclusionsShort-term deficits in physical functioning and other specific domains of QOL were observed following RRSO, but most women recovered baseline functioning by 6- and 12-month assessments. Issues regarding the potential impact of surgery on short-term sexual functioning should be considered and weighed carefully, particularly among younger women.
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