Evidence map›Paper›PMID 19141339›Full record

ReviewImmunology and allergy clinics of North America2009

Mechanism of eosinophilic esophagitis.

Anil Mishra

Open access · greenAbstract readReview
In one paragraph

Review in Immunology and allergy clinics of North America, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Dysmotility in Eosinophilic Esophagitis.Frontiers in pediatrics · 2022
    Review
  6. Significance of Interleukin (IL)-15 in IgE associated eosinophilic Esophagitis (EoE).International journal of basic and clinical immunology · 2019
    Article
  7. Monoclonal Antibodies for Treatment of Eosinophilic Esophagitis.Clinical reviews in allergy & immunology · 2018
    Review
  8. Food allergy and eosinophilic esophagitis in India: Lack of diagnosis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2016
    Article
  9. Role of Endoscopy in Diagnosis and Management of Pediatric Eosinophilic Esophagitis.Gastrointestinal endoscopy clinics of North America · 2016
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Esophageal functional impairments in experimental eosinophilic esophagitis.American journal of physiology. Gastrointestinal and liver physiology · 2012
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Anil MishraDepartment of Pediatrics, Division of Allergy and Immunology, 3333 Burnnet Avenue, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229, USA. anil.mishra@cchmc.org
Cincinnati Children's Hospital Medical Center · US

Funding

Role of IL-15 in the Pathogensis of Eosinophilic EsophagitisR01AI080581 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI MISHRA, ANIL · 2009 to 2023
$4.9M
Mechanistic Analysis of Eosinophilic Esophagitis.R01DK067255 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI MISHRA, ANIL · 2005 to 2014
$2.6M
NIAID NIH HHS R01 AI080581NIDDK NIH HHS R01 DK067255
6 · The paper itself

Abstract

Eosinophilic esophagitis (EoE) is a newly recognized disease and is an emerging entity throughout developing and developed countries, including the United States. Therefore, understanding the causes, natural history, diagnosis, and management is important for future therapeutic interventions. The pathogenesis of EoE is still not clear, but a growing body of evidence has established that this condition represents a T-cell-mediated immune response involving several proinflammatory mediators and chemoattractants known to regulate eosinophilic accumulation in the esophagus, such as IL-4, IL-5, IL-3 and eotaxin-1, -2, and -3. Determining the mechanism or mechanisms through which human esophageal-derived factors ultimately induce the functional abnormalities observed, and to which antigens patients who have EoE are sensitized that lead to the manifestation of symptoms, is of significant interest.

Indexed as

AllergensAnimalsAntibodies, MonoclonalChemotactic Factors, EosinophilDiet TherapyEosinophiliaEosinophilsEsophagitisFood HypersensitivityGlucocorticoidsHumansImmunity, CellularInterleukin-5Respiratory HypersensitivityT-LymphocytesAllergensAntibodies, MonoclonalChemotactic Factors, EosinophilGlucocorticoidsInterleukin-5

Identifiers

PMID19141339
PMCPMC2650237
OpenAlexW2155240779

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.