ArticleMarine biotechnology (New York, N.Y.)
Combining two-stage testing and interval mapping strategies to detect QTL for resistance to bonamiosis in the european flat oyster Ostrea edulis.
Article in Marine biotechnology (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Article
- Review
- Signatures of selection for bonamiosis resistance in European flat oyster (Evolutionary applications · 2019Article
- Genome-wide association analysis of nutrient traits in the oyster Crassostrea gigas: genetic effect and interaction network.BMC genomics · 2019Article
- Article
- Construction of a high-density genetic map and fine QTL mapping for growth and nutritional traits of Crassostrea gigas.BMC genomics · 2018Article
- Genomic Tools and Selective Breeding in Molluscs.Frontiers in genetics · 2018Review
- Genomic Selection in Aquaculture: Application, Limitations and Opportunities With Special Reference to Marine Shrimp and Pearl Oysters.Frontiers in genetics · 2018Review
- Genetic load in marine animals: a review.Current zoology · 2016Article
- Potential drivers of virulence evolution in aquaculture.Evolutionary applications · 2016Article
- Genetic variations of body weight and GCRV resistance in a random mating population of grass carp.Oncotarget · 2015Article
- Construction of an integrated map of Haliotis diversicolor using microsatellite markers.Marine biotechnology (New York, N.Y.) · 2012Article
- Article
- Linkage mapping of toll-like receptors (TLRs) in Japanese flounder, Paralichthys olivaceus.Marine biotechnology (New York, N.Y.) · 2011Article
- Mapping QTL for an adaptive trait: the length of caudal fin in Lates calcarifer.Marine biotechnology (New York, N.Y.) · 2011Article
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Authors and funding
8 authors.
Funding
Abstract
We have identified quantitative trait loci (QTL) in the flat oyster (Ostrea edulis) for resistance to Bonamia ostreae, a parasite responsible for the dramatic reduction in the aquaculture of this species. An F(2) family from a cross between a wild oyster and an individual from a family selected for resistance to bonamiosis was cultured with wild oysters injected with the parasite, leading to 20% cumulative mortality. Selective genotyping of 92 out of a total of 550 F(2) progeny (i.e., 46 heavily infected oysters that died and 46 parasite-free oysters that survived) was performed using 20 microsatellites and 34 amplification fragment length polymorphism primer pairs. Both a two-stage testing strategy and QTL interval mapping methods were used. The two-stage detection strategy had a high power with a low rate of false positives and identified nine and six probable markers linked to genes of resistance and susceptibility, respectively. Parent-specific genetic linkage maps were built for the family, spanning ten linkage groups (n = 10) with an observed genome coverage of 69-84%. Three QTL were identified by interval mapping in the first parental map and two in the second. Good concordance was observed between the results obtained after the two-stage testing strategy and QTL mapping.
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